U.S. patents available from 1976 to present.
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Treatment of fibromyalgia and related disorders

Patent 5895787 Issued on April 20, 1999. Estimated Expiration Date: Icon_subject October 8, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Inventor: Bristol ,   et al.

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Inventor: Sorensen

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Issued on: 01/13/1998
Inventor: Yue

Inventors

Assignee

Application

No. 954995 filed on 10/08/1997

US Classes:

514/415The bicyclo ring system consists of the five-membered hetero ring and a benzene ring (e.g., indole, etc.)

Examiners

Primary: Reamer, James H.

Attorney, Agent or Firm

International Class

A61K 031/405

Abstract

A method of treating fibromyalgia-like complaints (i.e., fibromyalgia, chronic fatigue syndrome and irritable bowel syndrome) in a patient, the method comprising: administering to the patient an 1H-indole-3-methanol compound (e.g., 1H-indole-3-methanol, ascorbigen, bis(3-indolyl) methane, indolo›3,2-b(carbazole)!, 2-(indol-3-ylmethyl)-3,3'-diindolylmethane, 5,6,11,12,17,18-hexahydrocyclonona›, 1,2-b;4,5-b';7,8-b"!triindole, 1H-indol-3-yl methoxy methane, ethoxy 1H-indol-3-yl ethoxy methane, other ethers of 1H-indole-3-methanol) in a medically acceptable manner in a pharmaceutically effective amount on a regular basis. It has been found that the administration of such indoles, particularly, 1H-indole-3-methanol, greatly mitigates the most severe symptoms of fibromyalgia. Patients with fibromyalgia have reported a decrease in pain, less fatigue, improved sleep patterns, and an improved sense of well being resulting from the oral administration of pharmaceutically effective amounts of an 1H-indole-3-methanol compound each day.

Other References

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