Curcumin (diferuloylmethane) inhibition of NF.kappa.B activation
Patent 5891924 Issued on April 6, 1999. Estimated Expiration Date: 
September 26, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
September 26, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesDiarylalkanoids having activity as lipoxygenase inhibitors Use of turmeric in wound healing Use of phosphotyrosine phosphatase inhibitors for controlling cellular proliferation Patent #: 5583242 InventorApplicationNo. 712932 filed on 09/26/1996US Classes:514/679Plural ringsExaminersPrimary: Criares, Theodore J.Attorney, Agent or FirmInternational ClassA61K 031/12AbstractThe present invention provides a method of inhibiting the activation of the NFκB transcription factor in an animal in need of such treatment comprising the step of administering to said animal a pharmacologically effective dose of curcumin. Also provided is a method of inhibiting the nuclear translocation of the p65 subunit of the NFκB transcription factor in a cell or in an animal in need of such treatment comprising the step of administering to said animal a pharmacologically effective dose of curcumin.Field of SearchPlural rings | |
