Methods for prevention and treatment of attention deficit disorder
Patent 5885998 Issued on March 23, 1999. Estimated Expiration Date: February 12, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
514/256, 1,3-diazines (e.g., pyrimidines, etc.)514/277, Hetero ring is six-membered consisting of one nitrogen and five carbon atoms514/344, Cyano bonded directly to the six-membered hetero ring514/357Nitrogen attached indirectly to the six-membered hetero ring by nonionic bonding
Patients susceptible to or suffering from attention deficit disorder are treated by administering an effective amount of an aryl subsistituted aliphatic compound, an aryl substituted olefinic amine compound or an aryl substituted acetylenic compound. Exemplary compounds are (E)-4-(5-pyrimidinyl)-3-butene-1-amine, (E)-4-3-(5-methoxypyridin)yl!-3-butene-1-amine, (E)-N-methyl-4-(5-pyrimidinyl)-3-butene-1-amine, (E)-N-methyl-4-3-(5-methoxypyrindin)yl!-3-butene-1-amine, (Z)-metanicotine, (E)-metanicotine, N-methyl-(3-pyridinyl)-butane-1-amine, N-methyl-4-(3-pyridinyl)-3-butyne-1-amine and (E)-N-methyl-4-3-(6-methylpyrindin)yl!-3-butene-1-amine.
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