U.S. patents available from 1976 to present.
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Attenuated canine parvovirus vaccine

Patent 5885585 Issued on March 23, 1999. Estimated Expiration Date: Icon_subject May 15, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Heterotypic canine parvovirus vaccine
Patent #: 4193990
Issued on: 03/18/1980
Inventor: Appel ,   et al.

Canine parvovirus vaccine
Patent #: 4193991
Issued on: 03/18/1980
Inventor: Appel ,   et al.

Modified living canine parvovirus vaccine
Patent #: 4303645
Issued on: 12/01/1981
Inventor: Carmichael ,   et al.

Canine parvovirus vaccines
Patent #: 4810494
Issued on: 03/07/1989
Inventor: Welsh

Subunit canine parvovirus vaccine Patent #: 4971793
Issued on: 11/20/1990
Inventor: Wood, et al.

Inventors

Assignee

Application

No. 647655 filed on 05/15/1996

US Classes:

424/204.1, Virus or component thereof424/186.1, Disclosed amino acid sequence derived from virus435/235.1, VIRUS OR BACTERIOPHAGE, EXCEPT FOR VIRAL VECTOR OR BACTERIOPHAGE VECTOR; COMPOSITION THEREOF; PREPARATION OR PURIFICATION THEREOF; PRODUCTION OF VIRAL SUBUNITS; MEDIA FOR PROPAGATING435/236, Inactivation or attenuation; producing viral subunits536/23.72Viral protein

Examiners

Primary: Achutamurthy, Ponnathapu
Assistant: Park, Hankyel T.

Attorney, Agent or Firm

Foreign Patent References

  • 554 414 A2 EP. 11/12/1993

International Classes

A61K 039/12
C12N 007/00
C12N 007/04
C07H 021/04

Abstract

The invention is directed to attenuated canine parvovirus (CPV) strains which may be used as a veterinary vaccine against CPV disease. The invention is further directed to a virus stock generated from a genomic DNA clone of the attenuated CPV strain which is used as a veterinary vaccine and is able to confer protective immunity to dogs against challenge with virulent CPV. Methods are given for the production of an attenuated CPV virus from a cloned CPV genome which may be used as a veterinary vaccine.

Other References

  • Parrish et al., Rapid Antigen-Type Replacement and DNA Sequence Evolution of Canine Parvovirus, J. Virol., vol. 65, No. 12, pp. 6544-6552, see p. 6545, left column , p. 6544, column 2, second full paragraph), Dec. 1991
  • Parrish, Emergence, Natural History, and Variation of Canine, Mink, and Feline Parvoviruses, Adv. Virus Res. 38:403-450, see pp. 419-423, 1990
  • Gruenberg et al., 1993, "Preparation and analysis of a molecular clone of an attenuated strain of canine parvovirus" Abstract, 5th Parvovirus Workshop, Nov. 10-14, 1993, Cyrstal River, Florida
  • Lopez de Turison et al., 1992, "Recombinant vaccine for canine parvovirus in dogs", J Virol 66(5):2748-2753
  • Saliki et al., 1992, "Canine parvovirus empty capsids produced by expression in a baculovirus vector: Use in analysis of viral properties and immunization of dogs", J Gen Virol 73:369-374
  • Parrish et al., 1991 "Mapping specific functions in the capsid structure of canine parvovirus and feline panleukipenia virus using infectious plasmid clones", Virology 183:195-205
  • Parrish et al., 1991, "Rapid antigenic-type replacement and DNA sequence evolution of canine parvovirus", J Virol 65(12):6544-6552
  • Parrish, 1990, "Emergence, natural history, and variation of canine, mink, and feline parvovirus", Adv Virus Res 38:403-450
  • Ausubel et al., 1989, Current Potocols in Molecular Biology, Greene Publshing Associates and Wiley Interscience, Chapter 8
  • Chang et al., 1988, "Multiple amino acids in the capsid structure of canine parvovirus coordinately determine the canine host range and specific antigenic and hemagglutination properties", J Virol 66(12):6858-6867
  • Mazzara et al., 1987, "Successful vaccination of dogs with empty capsids derived from canine parvovirus-bovine papillomavirus chimeric plasmids", Vaccines 87, Cold Spring Harbor Laboratory Press, pp. 419-424
  • Botstein and Shortle, 1985, "Strategies and applications of in vitro mutagenesis", Science 229:1193-1201
  • Parrish et al., 1984, "Characterization of antigenic variation among mink enteritis virus isolates", Am J Vet Res 45:2591-2599
  • Zoller and Smith, 1984, "Oligonucleotide-directed mutagenesis: A simple method using two oligonucliotide primers and a single stranded DNA template", DNA 3(6):479-488
  • Carmichael et al., 1983, "A modified live canine parvovirus vaccine II. Immune Response", Cornell Vet 73:13-29
  • Carmichael et al. 19881, "A modified live canine parvovirus strain with novel plaque characteristics I. Viral attenuation and dog response", Cornell Vet 71:408-427
  • Carmichael et al., 1980 "Hemagglutination by canine parvovirus: Serologic studies and diagnostic applications", Am J Vet Res 41(5):784-791
  • Appel et al., 1979, "Isolation and immunisation studies of a canine parvo-like virus from dogs with haemorrhagic enteritis", Vet Record 105:156-159
  • Bovarnick et al., 1950, "The influence of certain salts, amino acids, sugars, and proteins on the stability of rickettsiae", J Bact 59:509-522
  • Gruenberg et al., 1993, Poster Panels from an oral presentation given at the Fifth Parvovirus Workshop, Crystal City, Florida, Nov. 10-14, 1993
  • Churchill, 1987, "Preliminary Devleopment of a Live Attenuated Canine Parvovirus Vaccine from an isloate of British origin", The Veterinary Record 120:334-33
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