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Arylglycinamide derivatives and pharmaceutical compositions containing these compounds

Patent 5861509 Issued on January 19, 1999. Estimated Expiration Date: Icon_subject October 9, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3906100

Inventors

Assignee

Application

No. 947785 filed on 10/09/1997

US Classes:

544/130, Double bonded divalent chalcogen containing546/118, Three ring nitrogens in the bicyclo ring system546/190, Having -C(=X)-, wherein X is chalcogen, attached indirectly to a piperdine ring by nonionic bonding546/199, Plural ring nitrogens in the polycyclo ring system546/208, Ring nitrogen in the additional hetero ring546/210Plural ring nitrogens in the additional hetero ring

Examiners

Primary: Ramsuer, Robert W.

International Classes

A61K 031/445
A61K 031/535
C07D 295/145
C07D 413/04

Foreign Application Priority Data

1995-04-14 DE

Abstract

The invention relates to new arylglycinamide derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and Ar have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokin (tachykinin) antagonists.

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