Oligonucleotide libraries useful for producing primers
Patent 5858731 Issued on January 12, 1999. Estimated Expiration Date: 
February 20, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 20, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesProcess for DNA sequencing using oligonucleotide bank Method for producing the BGLI restriction endonuclease and methylase Isolated DNA encoding the NotI restriction endonuclease and related methods for producing the same Oligonucleotide families useful for producing primers Oligonucleotide libraries useful for producing primers Patent #: 5663062 InventorsApplicationNo. 313232 filed on 02/20/1996US Classes:435/91.1, Polynucleotide (e.g., nucleic acid, oligonucleotide, etc.)536/24.3, Probes for detection of specific nucleotide sequences or primers for the synthesis of DNA or RNA536/24.33, Primers536/25.3Synthesis of polynucleotides or oligonucleotidesExaminersPrimary: Horlick, Kenneth R.Attorney, Agent or FirmForeign Patent References
International ClassesC12P 019/34C07H 021/04 AbstractAn oligonucleotide library is described that is1 useful for producing an oligonucleotide of preselected sequence comprising a plurality of oligonucleotide members comprising one or more oligonucleotide species and having the compositional formula (X)a (N)b ; wherein X represents a non-degenerate nucleotide base and N represents a degenerate nucleotide base; "a" represents the number of non-degenerate nucleotide positions and is from 3 to 8; "b" represents the number of degenerate nucleotide positions and is from 0 to 4 but not greater that "a"; and wherein each of the oligonucleotide species is capable of forming a hybridization complex with at least one other of the oligonucleotide species in the library such that a single ligation event of the hybridization complex with another hybridization complex derived from the library produces a ligation reaction product comprising greater than 12 contiguous nucleotide base pairs.Other References
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