Primate embryonic stem cells
Patent 5843780 Issued on December 1, 1998. Estimated Expiration Date: 
January 18, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
January 18, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesApparatus and method for culturing embryonic stem cells Pluripotential embryonic stem cells and methods of making same Transduced mesenchymal stem cells Patent #: 5591625 InventorAssigneeApplicationNo. 591246 filed on 01/18/1996US Classes:435/363, Primate cell, per se435/366, Human435/373Method of co-culturing cellsExaminersPrimary: Woodward, Michael P.Assistant: Brumback, Brenda Attorney, Agent or FirmForeign Patent References
International ClassC12N 005/06AbstractA purified preparation of primate embryonic stem cells is disclosed. This preparation is characterized by the following cell surface markers: SSEA-1 (-); SSEA-3 (+); SSEA-4 (+); TRA-1-60 (+); TRA-1-81 (+); and alkaline phosphatase (+). In a particularly advantageous embodiment, the cells of the preparation have normal karyotypes and continue to proliferate in an undifferentiated state after continuous culture for eleven months. The embryonic stem cell lines also retain the ability, throughout the culture, to form trophoblast and to differentiate into all tissues derived from all three embryonic germ layers (endoderm, mesoderm and ectoderm). A method for isolating a primate embryonic stem cell line is also disclosed.Other References
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