Patent ReferencesMethod and composition for the preparation of controlled long-acting pharmaceuticals Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration Process for preparing ethyl ester of L-DOPA L-DOPA ethyl ester to treat Parkinson's disease Patent #: 5607969 InventorsAssignee
ApplicationNo. 678716 filed on 07/11/1996US Classes:514/538, Nitrogen bonded to carbon in Z moiety514/565, N-N or N=C(-N)-N containing (e.g., hydrazines, hydrazones, or quanidines, etc.)514/614, N-N containing (e.g., aminimine, hydrazine, etc.)514/654, The chain consists of two or more carbons which are unsubtituted or have acyclic hydrocarbyl substituents only514/657Bicyclo ring systemExaminersPrimary: Jarvis, William R. A.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/24A61K 031/195 A61K 031/16 A61K 031/135 AbstractThe present invention provides a pharmaceutical composition contains a thpeutically effective amount of L-DOPA ethyl ester and a carrier which comprises from 5.5 to 98.5% hydroxypropylmethyl cellulose, from 0.25 to 4.5% hydroxypropyl cellulose, and from 1 to 90% of a carboxyvinyl polymer.Field of SearchNitrogen bonded to carbon in Z moietyN-N or N=C(-N)-N containing (e.g., hydrazines, hydrazones, or quanidines, etc.) N-N containing (e.g., aminimine, hydrazine, etc.) The chain consists of two or more carbons which are unsubtituted or have acyclic hydrocarbyl substituents only Bicyclo ring system | |