U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Pharmaceutical composition of L-DOPA ester

Patent 5840756 Issued on November 24, 1998. Estimated Expiration Date: Icon_subject July 11, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method and composition for the preparation of controlled long-acting pharmaceuticals
Patent #: 4259314
Issued on: 03/31/1981
Inventor: Lowey

Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor
Patent #: 4424235
Issued on: 01/03/1984
Inventor: Sheth ,   et al.

Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
Patent #: 4680323
Issued on: 07/14/1987
Inventor: Lowey

Process for preparing ethyl ester of L-DOPA
Patent #: 5354885
Issued on: 10/11/1994
Inventor: Milman, et al.

L-DOPA ethyl ester to treat Parkinson's disease Patent #: 5607969
Issued on: 03/04/1997
Inventor: Milman, et al.

Inventors

Assignee

Application

No. 678716 filed on 07/11/1996

US Classes:

514/538, Nitrogen bonded to carbon in Z moiety514/565, N-N or N=C(-N)-N containing (e.g., hydrazines, hydrazones, or quanidines, etc.)514/614, N-N containing (e.g., aminimine, hydrazine, etc.)514/654, The chain consists of two or more carbons which are unsubtituted or have acyclic hydrocarbyl substituents only514/657Bicyclo ring system

Examiners

Primary: Jarvis, William R. A.

Attorney, Agent or Firm

Foreign Patent References

  • 0610595 EP. 08/13/1994

International Classes

A61K 031/24
A61K 031/195
A61K 031/16
A61K 031/135

Abstract

The present invention provides a pharmaceutical composition contains a thpeutically effective amount of L-DOPA ethyl ester and a carrier which comprises from 5.5 to 98.5% hydroxypropylmethyl cellulose, from 0.25 to 4.5% hydroxypropyl cellulose, and from 1 to 90% of a carboxyvinyl polymer.

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