Pulsatile drug delivery system
May 15, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesTime-controlled explosion systems and processes for preparing the same Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form Diltiazem formulations and methods of treatment Controlled absorption diltiazem formulation for once daily administration Multilayered controlled release pharmaceutical dosage form Controlled release potassium dosage form Extended release pharmaceutical formulations Pulsatile particles drug delivery system Controlled absorption diltiazen formulation for once-daily administration Patent #: 5616345 InventorAssigneeApplicationNo. 857105 filed on 05/15/1997US Classes:424/458, Containing discrete coated particles pellets, granules, or beads424/457, Sustained or differential release424/461, Containing polysaccharide (e.g., cellulose sugars, etc.)424/462, Containing solid synthetic polymers424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix424/494, Cellulose derivatives424/497, Containing solid synthetic polymers514/772.1, Aftertreated solid synthetic organic polymer (e.g., grafting, blocking, etc.)514/772.2, Polyvinyl alcohol514/772.3, Solid synthetic organic polymer514/777, Carbohydrate or lignin, or derivative514/778, Starch or derivative514/779, Algin or derivative514/781, Cellulose or derivative514/782, Natural gum or resin514/783, Plant extract or plant material of undetermined constitution514/786GlycerideExaminersPrimary: Page, Thurman K.Assistant: Spear, James M. Attorney, Agent or FirmInternational ClassesA61K 009/26A61K 009/58 A61K 009/60 A61K 009/62 AbstractA pulsatile drug delivery system comprising of a plurality of particles is able to deliver drug in any desired patterns. A plurality of particles with multi-layer core capable of short-pulse release interlaced with long-duration release is designed for delivery of multi-agents simultaneously or sequentially, or single agent, according to a pre-programmed profile.Field of SearchCapsules (e.g., of gelatin, of chocolate, etc.)Tablets, lozenges, or pills Coated (e.g., microcapsules) Cellulose derivatives Containing natural gums/resins Containing solid synthetic polymers Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof Containing discrete coated particles pellets, granules, or beads Containing polysaccharide (e.g., cellulose sugars, etc.) Containing solid synthetic polymers Discrete particles in supporting matrix Sustained or differential release Sustained or differential release type | |
