U.S. patents available from 1976 to present.
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Injectable bio-active glass in a dextran suspension

Patent 5840290 Issued on November 24, 1998. Estimated Expiration Date: Icon_subject May 30, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Bioglass coated A1203 ceramics
Patent #: 4103002
Issued on: 07/25/1978
Inventor: Hench ,   et al.

Method of bonding a bioglass to metal
Patent #: 4159358
Issued on: 06/26/1979
Inventor: Hench ,   et al.

Bonding of bone to materials presenting a high specific area, porous, silica-rich surface
Patent #: 4171544
Issued on: 10/23/1979
Inventor: Hench ,   et al.

Glass-ceramic dental restorations
Patent #: 4189325
Issued on: 02/19/1980
Inventor: Barrett ,   et al.

Bioglass coated metal substrate
Patent #: 4234972
Issued on: 11/25/1980
Inventor: Hench ,   et al.

Fluoride-containing Bioglass™ compositions
Patent #: 4775646
Issued on: 10/04/1988
Inventor: Hench ,   et al.

Injectable implant composition having improved intrudability
Patent #: 4803075
Issued on: 02/07/1989
Inventor: Wallace ,   et al.

Periodontal osseous defect repair
Patent #: 4851046
Issued on: 07/25/1989
Inventor: Low ,   et al.

Alkali-free bioactive sol-gel compositions
Patent #: 5074916
Issued on: 12/24/1991
Inventor: Hench, et al.

Injectable ceramic compositions and methods for their preparation and use
Patent #: 5204382
Issued on: 04/20/1993
Inventor: Wallace, et al.

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Inventors

Assignee

Application

No. 657713 filed on 05/30/1996

US Classes:

424/423, Surgical implant or material424/499, Contains proteins or derivative or polysaccharides or derivative428/402, Particulate matter (e.g., sphere, flake, etc.)428/402.24Microcapsule with solid core (includes liposome)

Examiners

Primary: Azpuru, Carlos

Attorney, Agent or Firm

International Classes

A61F 002/02
A61K 009/50
B32B 005/16

Abstract

The present invention relates to novel injectable aqueous suspensions of bio-active glass and dextrans for the repair of soft tissue or hard bone of mammals, especially in humans.

Other References

  • R. Dixon Walker et al., "Injectable Bioglass as a Potential Substitute For Injectable Polytetrafluoroethylene", The Journal of Urology, vol. 1, pp. 65-67, Aug. 1992
  • Larry L. Hench & June Wilson, "Advanced Series in Ceramics", An Introduction in Bioceramics, -- v1, pp. 1-24
  • Kirk-Othmer, "Concise Encyclopedia of Chemical Technology", 1985, pp. 104-106
  • John F. Buckley et al., Endoscopic Correction of Vesicoureteric Reflux with Injectable Microparticulate Silicone, "The Journal of Urology", Apr. 1992, v147-4, p356A
  • C.C. Shulman, MD, PhD, "Section on Urology Program for Scientific Sessions", The Journal of Urology, Oct., 1992, p. 85
  • Linda M. Kaairiki Shortliffe et al., "The Treatment of Urinary Incontinence by the Periurethral Implantation of Glutaraldehyde Dross-linked Collagen", The Journal of Urology, 1989 v141, pp. 538-541
  • E. A. Balazs et al., Marix engineering1991, v2, pp. 173-178
  • June Wilson et al., "Biomaterials for facial bone augmentation: Comparative studies",Applied Biomaterials, 1988, v22, (A2), pp. 159-177
  • Larry L. Hench et al, "Bonding Mechanisms at the Interface of Ceramic Prosthetic Material",J. Biomed, Mater, Res. Symposium, 1971, v2, (part 1) pp. 117-141
  • June Wilson et al., "Toxicology and biocompatibility of bioglasses", Journal of Biomedical Materials Research, 1981, v15, pp. 805-817
  • Larry L. Hench et al., "Direct Chemical Bond of Bioactive Glass-Ceramic Materials to Bone and Muscle", J. Biomed, Mater. Res. Symposium, 1973, v4, pp.25-4
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