Derivatives of triterpenoid acids and uses thereof.
Patent 5837690 Issued on November 17, 1998. Estimated Expiration Date: 
November 17, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 17, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3070623 3070624 18ଲ-Glycyrrhetinic acid amides useful as antiulcer agents 3ଲ-Hydroxy-18ଲ-olean-9-en-30-oic acids Complexes of glycerrhetinic acid with phospholipids and pharmaceutical and cosmetic compositions containing them Glycyrrhetic acid derivatives Method for inhibiting selectin-dependent adhesion of leukocytes and platelets by O-glycosylation modification Glycyrrhetinic acid derivatives Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (E-selectin) and LECAM-1 (L-selectin) Derivatives of triterpenoid acids and uses thereof InventorsAssigneeApplicationNo. 465893 filed on 06/06/1995US Classes:514/26, Cyclopentanohydrophenanthrene ring system424/1.45, Attached to cyclopentano-hydrophenanthrene (e.g., cholesterol, bile acid, steroids, cholane), hormone, or neurotransmitter, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator (e.g., T3, T4, insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine); derivative thereof424/9.1, IN VIVO DIAGNOSIS OR IN VIVO TESTING435/7.1, Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay514/885IMMUNE RESPONSE AFFECTING DRUGExaminersPrimary: Kight, JohnAssistant: Lee, Howard C. Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/705A61K 051/04 G01N 033/53 AbstractTriterpenoid acid derivatives are described that exhibit dual pharmacophobic activities, specifically selectin ligand and leukotriene biosynthetic inhibitory activities, and that thus have significant applications for the treatment or prevention of certain diseases including cancer and diseases associated with the inflammatory process as well as applications for the diagnosis of disease.Other References
Field of SearchCyclopentanohydrophenanthrene ring systemIMMUNE RESPONSE AFFECTING DRUG INTERFERON INDUCER Cyclopentanohydrophenanthrene ring system Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay Attached to cyclopentano-hydrophenanthrene (e.g., cholesterol, bile acid, steroids, cholane), hormone, or neurotransmitter, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator (e.g., T3, T4, insulin, human chorionic gonadotropin, intragonadal regulatory protein, Mullerian inhibiting substance, inhibin, epidermal growth factor, nerve growth factor, dopamine, norepinephrine); derivative thereof IN VIVO DIAGNOSIS OR IN VIVO TESTING |
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