Patent ReferencesTransdermal varapamil delivery device Anti-inflammatory analgesic adhesive preparation Anti-inflammatory analgesic adhesive preparation Externally applied antispasmatic products Preparation for percutaneous administration Transdermal laminated pharamaceutical compositions having prolonged effect and process for the preparation thereof Skin penetration enhancement using free base and acid addition salt combinations of active agents Patent #: 4888354 InventorsAssigneeApplicationNo. 655007 filed on 05/29/1996US Classes:424/448, Pressure sensitive adhesive means424/449, Transdermal or percutaneous424/486, Synthetic polymer424/487, Acrylic acid and derivatives514/818, ANESTHETIC, LOCAL514/821, ANTIARRHYTHMIC514/906, MUSCLE RELAXANT514/929VASODILATORExaminersPrimary: Page, Thurman K.Assistant: Shelborne, Kathryne E. Attorney, Agent or FirmForeign Patent References
International ClassesA61F 013/02A61K 009/14 Foreign Application Priority Data1989-03-15 JPAbstractMedicated plasters composed of a flexible support and a pressure-sensitive adhesive layer laminated thereon, in which said pressure-sensitive adhesive layer has an exposed surface with pH of 7 or higher and contains one of the following three components:i) a basic physiologically active agent and an acidic substance,ii) a salt of a basic physiologically active agent and a basic substance, andiii) a basic physiologically active agent and a salt of a basic physiologically active agent.Other References
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