Patent ReferencesPolymeric orthoesters housing beneficial drug for controlled release therefrom Poly(carbonates) Polymeric orthoesters Topical therapeutic preparations Compositions comprising arylene substituted poly(orthoesters) containing useful agents Polymers of di- (and higher functionality) ketene acetals and polyols Acrylate and methacrylate monoesters of pentaerythritol and pentaerythritol orthoesters and polymers and copolymers derived therefrom Bioerodible poly(ortho ester) thermoplastic elastomer from diketene diacetal Silicone elastomer transdermal matrix system Bioerodible polymers useful for the controlled release of therapeutic agents Patent #: 5030457 InventorsAssigneeApplicationNo. 226279 filed on 04/11/1994US Classes:424/486, Synthetic polymer424/423, Surgical implant or material424/457, Sustained or differential release514/179, Modified C-ring (except methyl in 13-position) (e.g., double bond containing, substituted, etc.)528/425FROM ORGANIC OXYGEN-CONTAINING REACTANTExaminersPrimary: Mosley, TerressaForeign Patent References
International ClassA23P 001/00Foreign Application Priority Data1990-08-28 CAAbstractBioerodible ortho ester polymers useful for preparing bioerodible pharmaceutical compositions such as implants, ointments, creams, gels and the like are provided. The pharmaceutical compositions of the invention are useful for the controlled release of therapeutic agents, and may be administered for a variety of purposes, such as for the treatment of deep wounds, including burns, and for the treatment of periodontal disease. | |