Composition and method of treating depression using naloxone or naltrexone in combination with a serotonin reuptake inhibitor
Patent 5817665 Issued on October 6, 1998. Estimated Expiration Date: 
November 20, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 20, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPiperidine opioid antagonists Patent #: 5064834 InventorAssigneeApplicationNo. 560820 filed on 11/20/1995US Classes:514/282, One of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.)514/253.04, Bicyclo ring having the additional six-membered nitrogen hetero ring as one of the cyclos514/321, Plural hetero atoms in the polycyclo ring system514/410, Polycyclo ring system having the five-membered hetero ring as one of the cyclos514/649, Amino nitrogen attached to aryl ring or aryl ring system by an acyclic carbon or acyclic chain514/651, Ether oxygen is part of the chain514/657Bicyclo ring systemExaminersPrimary: Jarvis, William R. A.Attorney, Agent or FirmInternational ClassesA61K 031/44A61K 031/495 A61K 031/445 A61K 031/135 AbstractThis invention relates to a composition and method for treating depression by administering to a patient a pharmacologically effective dose of an opioid antagonist having a pentacyclic nucleus structurally analogous to naltrexone, and a pharmacologically effective dose of a nontricyclic antidepressantField of SearchPolycyclo ring system having the five-membered hetero ring as one of the cyclosOne of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.) Amino nitrogen attached to aryl ring or aryl ring system by an acyclic carbon or acyclic chain Bicyclo ring system Ether oxygen is part of the chain Plural hetero atoms in the polycyclo ring system | |
