U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Pharmaceutical compositions containing famotidine and aluminum hydroxide or magnesium hydroxide

Patent 5817340 Issued on October 6, 1998. Estimated Expiration Date: Icon_subject November 25, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3048526

3922338

Simethicone antacid tablet
Patent #: 4198390
Issued on: 04/15/1980
Inventor: Rider

Guanidinothiazole compounds, process for preparation and gastric inhibiting compositions containing them
Patent #: 4283408
Issued on: 08/11/1981
Inventor: Hirata ,   et al.

Taste masking and sustained release coatings for pharmaceuticals
Patent #: 5075114
Issued on: 12/24/1991
Inventor: Roche

Controlled release article with pulsatile release
Patent #: 5213808
Issued on: 05/25/1993
Inventor: Bar-Shalom, et al.

Methods and pharmaceutical compositions for treating episodic heartburn
Patent #: 5229137
Issued on: 07/20/1993
Inventor: Wolfe

Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets Patent #: 5260072
Issued on: 11/09/1993
Inventor: Roche, et al.

Inventors

Assignee

Application

No. 756080 filed on 11/25/1996

US Classes:

424/470, Where particles are granulated424/455, Containing emulsions, dispersions, or solutions424/464, Tablets, lozenges, or pills424/472, Layered unitary dosage forms424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/490, Coated (e.g., microcapsules)424/493, Containing polysaccharides (e.g., sugars)424/494, Cellulose derivatives424/495, Ethyl cellulose424/497, Containing solid synthetic polymers424/498, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof424/687, Calcium carbonate424/690, Aluminum hydroxide424/692, Magnesium hydroxide or oxide514/370Nitrogen bonded directly to ring carbon of the thiazole ring

Examiners

Primary: Cintins, Marianne M.
Assistant: Moezie, M.

Attorney, Agent or Firm

Foreign Patent References

  • 0 294 933 A3 EP. 04/13/1988
  • 0286781 A2 EP. 10/13/1988
  • 0 290 229 B1 EP. 07/13/1991
  • WO 92/00102 WO. 06/13/1991

International Classes

A61K 009/26
A61K 009/16
A61K 009/50

Abstract

A solid oral dosage form for the treatment of gastrointestinal disorders comprising a therapeutically effective amount of a therapeutically effective amount of guanidinothiazole compound; and a therapeutically effective amount of an antacid wherein the pharmaceutical and an antacid are separated by a barrier which is substantially impermeable to an antacid.

Other References

  • "The Dating Game", text of speech given at The Proprietary Assn.'s Twelfth Manufacturing Controls Seminar, Cherry Hill, NJ. Oct. 5-6, 1978 by Joel S. Davis, Chief, Prod. Quality Branch, FDA, pp. 1-15
  • Physician's Desk Reference, 45th ed., Medical Economics Co., Oradell, NJ, pp. 1478-1479 (1991)
  • "Organic Chemistry," Morrison et al., Allyn and Bacon, Inc., Boston, 1973, pp. 55-5
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