U.S. patents available from 1976 to present.
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Relaxin analogs and derivatives methods and uses thereof

Patent 5811395 Issued on September 22, 1998. Estimated Expiration Date: Icon_subject September 22, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Molecular cloning and characterization of a further gene sequence coding for human relaxin
Patent #: 5023321
Issued on: 06/11/1991
Inventor: Hudson, et al.

Use of relaxin in cardiovascular therapy
Patent #: 5166191
Issued on: 11/24/1992
Inventor: Cronin, et al.

Human relaxin polypeptides
Patent #: 5179195
Issued on: 01/12/1993
Inventor: Hudson, et al.

Human relaxin formulation
Patent #: 5451572
Issued on: 09/19/1995
Inventor: Cipolla, et al.

Use of relaxin in the treatment of bradycardia Patent #: 5478807
Issued on: 12/26/1995
Inventor: Cronin, et al.

Inventors

Assignee

Application

No. 483476 filed on 06/07/1995

US Classes:

514/12, 25 or more peptide repeating units in known peptide chain structure514/21, Produced by or extracted from animal tissue530/324, 25 or more amino acid residues in defined sequence530/399Hormones, e.g., prolactin, thymosin, growth factors, etc.

Examiners

Primary: Robinson, Douglas W.
Assistant: Touzeau, P. Lynn

Attorney, Agent or Firm

International Classes

A61K 038/16
A61K 038/17
C07K 007/10

Abstract

The present invention relates to a relaxin analogs and derivatives, and uses thereof. The present invention further relates to compositions comprising a relaxin analogs and derivatives, and relaxin wherein such composition exhibits an additive or synergistic effect.

Other References

  • Bani et al., 1994, "Differentation of breast cancer cells in vitro is promoted by the concurrent influence of myoepithelial cells and relaxin," Bio J. Cancer 70:900-904
  • Bryant-Greenwood, 1982, Endocrine Reviews 3:62-90
  • Bullesbach and Schwabe, 1991, J. Biol. Chem. 266:10754-10761
  • Burkhardt et al., 1994, Genomics 20:13-19
  • Osheroff et al., 1990, The Journal of Biological Chemistry 265:9396-9401
  • Stemmermann et al., 1994, Journal of Endocrinology 140:321-32
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