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Method for improving disturbed behavior and elevating mood in humans

Patent 5804592 Issued on September 8, 1998. Estimated Expiration Date: Icon_subject May 30, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Cannabinoid receptor antagonists Patent #: 5596106
Issued on: 01/21/1997
Inventor: Cullinan, et al.

Inventor

Assignee

Application

No. 866511 filed on 05/30/1997

US Classes:

514/454, Tricyclo ring system having the hetero ring as one of the cyclos514/221Bicyclo ring system having the seven-membered hetero ring as one of the cyclos

Examiners

Primary: Schenkman, Leonard

Attorney, Agent or Firm

International Class

A61K 031/35

Abstract

A method for improving disturbed behavior and negative mood in animals suffering from dementia, particularly humans suffering from Alzheimer's type dementia, by administration of dronabinol.

Other References

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  • Beal et al., Dronabinol as a Treatment for Anorexia Associated with Weight Loss in Patients with Aids, Journal of Pain and Symptom Management 10:89-97 (1995)
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  • Robert Gorter, M.D., Measurement of Anorexia-Cachexia Associated With Cancer and HIV Infection Oncology 5:13-17 (1991)
  • Agurell et al., Pharmacokinetics and Metabolism of Ɗ1 -Tetrahydrocannabinol and Other Cannabinoids with Emphasis on Man*, Pharmacological Reviews, 38:21-43, (1986)
  • Dackis et al., Persistence of Urinary Marijuana Levels After Supervised Abstinence, Am J Psychiatry 139:1196-11989 (1982)
  • Lawton et al., Observed Affect In Nursing Home Residents With Alzheimer's Disease, Journal of Gerontology: Psychological Sciences, 51B:P3-P14 (1996)
  • McKhann et al., Clinical Diagnosis of Alzheimer's Disease: Report of the NINCDS-ADRADA Work Group* Under The Auspices of Department of Health and Human Services Task Force on Alzheimer's Disease, Neurology, 34:939-944 (1984)
  • Cohen-Mansfield et al., A Description of Agitation in a Nursing Home, Journal of Gerontology: Medical Sciences, 44:M77-84 (1989)
  • Lawton et al., Relationship of Events and Affect in the Daily Life of an Elderly Population, Psychology and Aging, 10:469-477 (1995
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