Identification of an exogenous intra-erythrocytic bacterium in patients having systemic lupus erythematosus, and treatment
Patent 5795563 Issued on August 18, 1998. Estimated Expiration Date: 
December 13, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 13, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesDiagnostic method for detection of systemic lupus erythematosus Method of detecting cytopenia that is mediated by drug-dependent antibody binding to blood cells Patent #: 5585243 InventorAssigneeApplicationNo. 763709 filed on 12/13/1996US Classes:424/9.361, Heterocyclic compound is attached to or complexed with the metal424/9.362, Porphyrin or derivative thereof424/9.363, Hetero ring contains at least eight members514/192, 1-thia-4-aza-bicyclo (3.2.0) heptane ring containing (including dehydrogenated) (e.g., penicillins, etc.)514/199, Penicillin G per se or salt thereof (e.g., procaine pencillin G, etc.)514/2001-thia-5-aza-bicyclo (4.2.0) octane ring containing (including dehydrogenated) (e.g., cephalosporins, etc.)ExaminersPrimary: Weddington, Kevin E.Attorney, Agent or FirmInternational ClassesA61K 049/00A61K 031/43 AbstractIntra-erythrocytic exogenous bacterial structures or parasites seen by giemsa and phase contrast microscopy in several patients with systemic lupus erythematosus (SLE) and not in controls were identified as bacteria. Treatment of an SLE patient is contemplated with an antibacterial amount of a rifamycin in conjunction with an antibacterial amount of either a macrolide such as clarithromycin or a third generation cephalosporin such as cefpodoxime that is itself more preferably used in conjunction with an adjuvant amount of probenecid.Other References
Field of SearchHeterocyclic compound is attached to or complexed with the metalPorphyrin or derivative thereof Hetero ring contains at least eight members 1-thia-4-aza-bicyclo (3.2.0) heptane ring containing (including dehydrogenated) (e.g., penicillins, etc.) Penicillin G per se or salt thereof (e.g., procaine pencillin G, etc.) 1-thia-5-aza-bicyclo (4.2.0) octane ring containing (including dehydrogenated) (e.g., cephalosporins, etc.) | |
