U.S. patents available from 1976 to present.
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Substituted oxazolidinones

Patent 5792765 Issued on August 11, 1998. Estimated Expiration Date: Icon_subject February 3, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
Patent #: 4705799
Issued on: 11/10/1987
Inventor: Gregory

Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
Patent #: 4801600
Issued on: 01/31/1989
Inventor: Wang ,   et al.

Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
Patent #: 4942183
Issued on: 07/17/1990
Inventor: Gregory, et al.

Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
Patent #: 4965268
Issued on: 10/23/1990
Inventor: Wang, et al.

Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
Patent #: 5032605
Issued on: 07/16/1991
Inventor: Wang, et al.

5'Indolinyl-5ଲ-amidomethyloxazolidin-2-ones
Patent #: 5164510
Issued on: 11/17/1992
Inventor: Brickner

Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
Patent #: 5254577
Issued on: 10/19/1993
Inventor: Carlson, et al.

Oxazolidone derivative
Patent #: 5475014
Issued on: 12/12/1995
Inventor: Akasaka, et al.

Benzoxazolyl- and benzothiazolyloxazolidinones
Patent #: 5529998
Issued on: 06/25/1996
Inventor: Habich, et al.

Adhesion receptor antagonists III
Patent #: 5561148
Issued on: 10/01/1996
Inventor: Gante, et al.

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Inventors

Application

No. 794034 filed on 02/03/1997

US Classes:

514/236.8, Ring chalcogen in the additional hetero ring (e.g., oxazole, etc.)514/252.06, Polycyclo ring system having the additional five-membered hetero ring as one of the cyclos514/256, 1,3-diazines (e.g., pyrimidines, etc.)514/331, Nitrogen attached indirectly to the piperidine ring by nonionic bonding514/340, Ring nitrogen in the additional hetero ring (e.g., oxazole, etc.)514/365, 1,3-thiazoles (including hydrogenated)514/367, Bicyclo ring system having the thiazole ring as one of the cyclos514/374, 1,3-oxazoles (including hydrogenated)544/137, The five-membered hetero ring has at least oxygen and nitrogen as ring hetero atoms544/238, 1,2-diazines which contain an additional hetero ring544/324, Additional hetero ring which is unsaturated544/369, 1,3-oxazole ring or 1,3-thiazole ring (including hydrogenated)544/405, Additional hetero ring which is unsaturated546/208, Ring nitrogen in the additional hetero ring546/256, Additional hetero ring containing546/271.4, 1,3-oxazoles (including hydrogenated)548/171, Nitrogen bonded directly to the -C(=X)- group548/178, Chalcogen or nitrogen attached directly to the other cyclo of the bicyclo ring system by nonionic bonding548/196, Chalcogen or additional nitrogen bonded directly to the -C(=X)- group548/215, 1,3-oxazoles (including hydrogenated)548/217, Polycyclo ring system having the oxazole ring as one of the cyclos548/221, Chalcogen bonded directly at the 2-position of the oxazole ring548/231, 3-position substituent contains ethylenic or acetylenic unsaturation or nitrogen548/235Plural double bonds between the ring members of the oxazole ring

Examiners

Primary: Dees, Jose G.
Assistant: Lutz, Laura R. C.

Attorney, Agent or Firm

Foreign Patent References

  • 352781 EP. 01/13/1990
  • 609441 EP. 08/13/1994
  • 694543 EP. 01/13/1996
  • 693491 EP. 01/13/1996
  • 4425609 DE. 01/13/1996

International Classes

A61K 031/42
C07D 413/14

Foreign Application Priority Data

1996-02-06 DE

Abstract

The present invention relates to new substituted oxazolidinones of the general formula (1) ##STR1## in which the substituents have the meaning indicated in the description, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.

Other References

  • E.A. ter Laak, Antimicrobial Agents and Chemotherapy, vol. 35, No. 2, pp. 228-233 (1991)
  • J. Swenson et al, Antimicrobial Agents and Chemotherapy, vol. 21, No. 2, pp. 182-192 (1982)
  • C. Park et al, J.Med.Chem., vol. 35, pp. 1156-1165 (1992
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