Patent ReferencesIntra-pocket drug delivery devices for treatment of periodontal diseases Injectable drug delivery system and method Patent #: 5620700 Inventors
AssigneeApplicationNo. 843682 filed on 04/10/1997US Classes:424/426, Errodable, resorbable, or dissolving424/435, Mouth523/105, Nonmedicated composition specifically intended for contact with living animal tissue or process of preparing; other than apparel523/113Composition suitable for use as tissue or body member replacement, restorative, or implantExaminersPrimary: Azpuru, CarlosAttorney, Agent or FirmInternational ClassesA61F 002/02A61K 006/00 AbstractThe present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days. | |