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US Patent 5753259 - Method of preparing controlled-release preparations for biologically active materials and resulting compositions
US Patent Issued on May 19, 1998
Estimated Patent Expiration Date:
May 19, 2015Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
May 19, 2015Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractA method and product for preparing a controlled-release composition are provided. The method comprises formation of a mixture containing at least one amphiphilic substance capable of forming a liquid crystalline phase, in contact with a liquid selected from the group consisting of water, glycerol, ethylene glycol, propylene glycol and mixtures thereof. The method includes a step of providing in such mixture a bioactive material.Other References
| InventorsAssigneeApplicationNo. 313543 filed on 09/27/1994US Classes:424/50, Ferment containing (e.g., enzymes, bacteria, etc.)264/4.1, Liquid encapsulation utilizing an emulsion or dispersion to form a solid-walled microcapsule (includes liposome)264/4.3, With treatment subsequent to solid wall formation (e.g., coating, hardening, etc.)264/4.6Solid-walled microcapsule formed by physically removing a constituent (e.g., evaporation, extraction, etc.)Field of Search264/4.1, Liquid encapsulation utilizing an emulsion or dispersion to form a solid-walled microcapsule (includes liposome)264/4.3, With treatment subsequent to solid wall formation (e.g., coating, hardening, etc.)264/4.6, Solid-walled microcapsule formed by physically removing a constituent (e.g., evaporation, extraction, etc.)428/402.2, Microcapsule with fluid core (includes liposome)424/84, BAITS, ATTRACTANTS, OR LURES (NON-FOOD)424/450, Liposomes424/498, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof424/502, Contains waxes, higher fatty acids, higher fatty alcohols436/829, LIPOSOMES (E.G., ENCAPSULATION, ETC.)514/963, Microcapsule-sustained or differential release514/965Discrete particles in supporting matrixExaminersPrimary: Kishore, Gollamudi S.Attorney, Agent or FirmUS Patent References4073943, Method of enhancing the administration of pharmalogically active agentsIssued on: 02/14/1978 Inventor: Wretlind , et al.4115313, Bile acid emulsions Issued on: 09/19/1978 Inventor: Lyon , et al.4145410, Method of preparing a controlled-release pharmaceutical preparation, and resulting composition Issued on: 03/20/1979 Inventor: Sears4156719, Compositions for rectal use Issued on: 05/29/1979 Inventor: Sezaki , et al.4217344, Compositions containing aqueous dispersions of lipid spheres Issued on: 08/12/1980 Inventor: Vanlerberghe , et al.4235871, Method of encapsulating biologically active materials in lipid vesicles Issued on: 11/25/1980 Inventor: Papahadjopoulos , et al.4241046, Method of encapsulating biologically active materials in lipid vesicles Issued on: 12/23/1980 Inventor: Papahadjopoulos , et al.4323556, Solid formulations containing pheromones and method of using same Issued on: 04/06/1982 Inventor: Dal Moro , et al.4331654, Magnetically-localizable, biodegradable lipid microspheres Issued on: 05/25/1982 Inventor: Morris4377567, Lipid membrane drug delivery Issued on: 03/22/1983 Inventor: Geho4789633, Fused liposome and acid induced method for liposome fusion Issued on: 12/06/1988 Inventor: Huang , et al.5143934, Method and composition for controlled delivery of biologically active agents Issued on: 09/01/1992 Inventor: Lading, et al.5151272, Method of preparing controlled-release preparations for biologically active materials and resulting compositions Issued on: 09/29/1992 Inventor: Engstrom, et al.5262164Sustained release compositions for treating periodontal disease Issued on: 11/16/1993 Inventor: Damani Foreign Patent References
International ClassA61K 009/127Foreign Application Priority Data1982-11-26 SE |
