U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

High buffer-containing enteric coating digestive enzyme bile acid compositions and method of treating digestive disorders therewith

Patent 5750104 Issued on May 12, 1998. Estimated Expiration Date: Icon_subject May 29, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Re30910

3004893

Preparation of enteric coated digestive enzyme compositions
Patent #: 4079125
Issued on: 03/14/1978
Inventor: Sipos

Gallstone dissolution compositions and method
Patent #: 4264583
Issued on: 04/28/1981
Inventor: Jandacek

Process for the production of pancreatin pellets
Patent #: 4280971
Issued on: 07/28/1981
Inventor: Wischniewski ,   et al.

Enzyme-containing digestive aid compostions
Patent #: 4447412
Issued on: 05/08/1984
Inventor: Bilton

Composition and methods for alleviating cystic fibrosis
Patent #: 4826679
Issued on: 05/02/1989
Inventor: Roy

Cylindrical microtablets
Patent #: 4828843
Issued on: 05/09/1989
Inventor: Pich ,   et al.

Pancreatic enzyme products and a process for the preparation thereof
Patent #: 4859471
Issued on: 08/22/1989
Inventor: Fulberth ,   et al.

Process for micronizing slightly-soluble drug
Patent #: 5202129
Issued on: 04/13/1993
Inventor: Samejima, et al.

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Inventor

Assignee

Application

No. 654900 filed on 05/29/1996

US Classes:

424/94.21Pancreatin

Examiners

Primary: Kulkosky, Peter F.

Attorney, Agent or Firm

Foreign Patent References

  • 1296944 GB. 11/13/1972
  • 1362365 GB. 04/13/1974

International Class

A61K 038/43

Abstract

Disclosed are gastric acid-resistant polymer-coated buffered digestive enzymes/bile acid compositions, process for their preparations and methods of treating digestive disorders and cystic fibrosis by administering said compositions to a mammal in need of such treatment.

Other References

  • The Journal of Pediatrics, vol. 17, No. 3, Sep. 1990:482-9, Effects of ursodeoxycholic acid therapy for liver disease associated with cystic fibrosis
  • GUT, vol. 31; No. 8, 1990, 918-921, Effects of ursodeoxycholic acid treatment on nutrition and liver. function in patients with cystic fibrosis and longstanding cholestasis
  • Bile Acids: 1993 and The Future, Mar. 11-14, 1993, Palm Desert, Ca, Ed. C.J. Steev, J. R. Bloomer & N.F. La Russo, Univ. of Minnesota, Dept. 0f Medicine, Bile Acid Therapy in the Management of Chronic Cholestasis in the Pediatric Patient
  • G.J. Peschke, "Pancreatic Enzymes in Health and Disease", Springer Verlag Berlin Heidelberg, 1991, pp. 55-6
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