Method and device for moving molecules by the application of a plurality of electrical fields
March 13, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMethod and apparatus for dielectrophoretic manipulation of chemical species Gas chromatography system and detector and method Miniature gas chromatograph apparatus Coating for electrophoresis tube Pulsed-field gradient gel electrophoretic apparatus Ampholyte separation method and apparatus Chromatographic separation device Silicon semiconductor wafer for analyzing micronic biological samples Electrophoresis apparatus Miniature devices useful for gas chromatography Patent #: 4935040 InventorsAssigneeApplicationNo. 615642 filed on 03/13/1996US Classes:204/454, With adjustment or alteration of electro-osmotic bulk flow204/451, Capillary electrophoresis204/547, Dielectrophoresis (i.e., using nonuniform electric field)204/601, Capillary electrophoresis type204/643Dielectrophoretic (i.e., uses nonuniform electric field)ExaminersPrimary: Gorgos, KathrynAssistant: Starsiak, John S. Jr. Attorney, Agent or FirmForeign Patent References
International ClassesG01N 027/26G01N 027/447 AbstractDevices and methods are disclosed for moving charged molecules through a medium by the application of a plurality of electrical fields of sufficient strength and applied for sufficient amounts of time so as to move the charged molecules through the medium. The devices although preferably small in size, preferably generate large numbers (100 or more) of electrical fields to a movement area which preferably contains a liquid buffered or gel medium. Mixtures of charged molecules are pulled through the gel by the force of the electrical fields. The fields are preferably activated simultaneously or sequentially one after another at various speeds to create complex force field distributions or moving field waves along the separation medium. Charged molecules capable of moving quickly through the gel will be moved along by the faster moving field waves and be separated from slower moving molecules. The fields can be activated by computer software and can be used to move molecules away from and toward each other to obtain rapid and complex chemical synthesis, sequencing or reaction protocols.Other References
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