U.S. patents available from 1976 to present.
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Inhibitors of factor Xa

Patent 5721214 Issued on February 24, 1998. Estimated Expiration Date: Icon_subject June 7, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Peptide aldehydes as antithrombotic agents
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More ...

Inventors

Assignee

Application

No. 485433 filed on 06/07/1995

US Classes:

514/18, 3 or 4 peptide repeating units in known peptide chain514/19, 2 peptide repeating units in known peptide chain530/331Tripeptides, e.g., tripeptide thyroliberin (TRH), melanostatin (MIF), etc.

Examiners

Primary: Tsang, Cecilia J.
Assistant: Harle, Jennifer

Attorney, Agent or Firm

Foreign Patent References

  • 0 045 665 A1 EP. 02/13/1982
  • 0 195 212 A3 EP. 09/13/1986
  • 0 275 101 A3 EP. 07/13/1988
  • 0 352 903 A2 EP. 01/13/1990
  • 0 364 344 A3 EP. 04/13/1990
  • 0 410 411 A2 EP. 01/13/1991
  • 0 417 721 A2 EP. 03/13/1991
  • 0 479 489 A2 EP. 04/13/1992
  • 0 504 064 A1 EP. 09/13/1992
  • 0 643 073 A1 EP. 03/13/1995
  • A 648780 EP. 04/13/1995
  • 6-327488 JP. 11/13/1994
  • WO 93/14779 WO. 08/13/1993
  • WO 93/15756 WO. 08/13/1993
  • WO 94/08941 WO. 04/13/1994
  • WO 94/13693 WO. 06/13/1994
  • WO 94/25051 WO. 11/13/1994
  • WO 95/09634 WO. 04/13/1995
  • WO 96/19493 WO. 06/13/1996

International Classes

A61K 038/00
C07K 038/06
C07K 005/00
C07K 007/00

Abstract

Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.

Other References

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