Compositions and methods of treating HIV with d4T, 5-fluorouracil/tegafur, and uracil
Patent 5719132 Issued on February 17, 1998. Estimated Expiration Date: June 27, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
514/50, 2,4-diketone pyrimidine or derivative (e.g., uracil, etc.)514/274, Chalcogen bonded directly to pyrimidine at 2-position536/28.55, Halogen bonded directly to the 5-position of the diazine ring (e.g., 5-fluorouridine, etc.)544/309, At 2-position and at 4- or 6-position544/310, Additional hetero ring which is unsaturated544/313Halogen attached directly to the diazine ring by nonionic bonding
The present invention is directed to the use of pharmaceutical compositions containing anti-retroviral effective amounts of (a) d4T and (b) 5-fluorouracil or a prodrug, or salt thereof.
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