Nanoparticles containing the R(-)enantiomer of ibuprofen
Patent 5718919 Issued on February 17, 1998. Estimated Expiration Date: 
February 24, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 24, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesDosage form for delivering acetaminophen or phenylpropanolamine Onset-hastened/enhanced antipyretic response S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form Selective precipitation of -aryl carboxylic acid salts Patent #: 5399707 InventorsApplicationNo. 393648 filed on 02/24/1995US Classes:424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/470, Where particles are granulated424/488, Polysaccharides (e.g., cellulose, etc.)424/490Coated (e.g., microcapsules)ExaminersPrimary: Page, Thurman K.Assistant: Benston, William E. Jr. Attorney, Agent or FirmInternational ClassA61K 009/16AbstractThere is described a composition comprised of nanoparticles of a therapeutic agent having a surface modifier adsorbed on the surface thereof. The present composition is characterized in that the therapeutic agent is ibuprofen or fenoprofen which is substantially enriched in the R(-) enantiomer.Field of SearchParticulate form (e.g., powders, granules, beads, microcapsules, and pellets)Coated (e.g., microcapsules) Layered unitary dosage forms Polysaccharides (e.g., cellulose, etc.) Carboxyl, or salt thereof, not bonded directly to ring Carboxy or salt thereof only attached indirectly to the benzene ring | |
