U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Bioadhesive polyethylene glycol ointment for medicaments

Patent 5714165 Issued on February 3, 1998. Estimated Expiration Date: Icon_subject February 3, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Re33093

Topical treatment of aphthous stomatitis
Patent #: 4307075
Issued on: 12/22/1981
Inventor: Martin

Anticalculus oral composition
Patent #: 4627977
Issued on: 12/09/1986
Inventor: Gaffar ,   et al.

Buccal drug dosage form
Patent #: 4764378
Issued on: 08/16/1988
Inventor: Keith ,   et al.

Adhesive medical tapes for oral mucosa
Patent #: 4765983
Issued on: 08/23/1988
Inventor: Takayanagi ,   et al.

Gel bases for pharmaceutical compositions
Patent #: 4883660
Issued on: 11/28/1989
Inventor: Blackman, et al.

Adhesive composition
Patent #: 4910247
Issued on: 03/20/1990
Inventor: Haldar, et al.

Muco-bioadhesive composition Patent #: 4948580
Issued on: 08/14/1990
Inventor: Browning

Inventors

Assignee

Application

No. 861558 filed on 04/01/1992

US Classes:

424/486, Synthetic polymer514/928, Topical514/944, GEL514/969OINTMENT OR SALVE BASE

Examiners

Primary: Webman, Edward J.

Attorney, Agent or Firm

Foreign Patent References

  • 203613 JP. 08/13/1988

International Classes

A61K 009/06
A61K 047/32
A61K 047/34
A61K 009/10

Abstract

A therapeutic composition having wet adherent properties and particularly useful for delivery of medicaments to mucosal surfaces comprises a therapeutically effective amount of a medicament dispersed in a base material comprising from about 3 to 15% by weight of a water soluble salt of a copolymer of methyl vinyl ether and maleic acid or anhydride and from about 85 to 97% by weight of polyethylene glycol. Formulations of the base material with triamcinolone acetonide and lidocaine are particularly efficacious in the treatment of recurrent aphthous ulcers.

Other References

  • "Topical Mucosal Adhesive Dosage Forms", T. Nagi, Medicinal Research Reviews, vol. 6, No. 2,227-242 (1986
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