Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof
January 13, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2516438 3767437 Process of degrading and regenerating bone and tooth material and products Method for making collagen sponge Dental cement containing poly(carboxylic acid), chelating agent and glass cement powder Medicinally useful, shaped mass of collagen resorbable in the body Bone morphogenetic protein process Bone graft material for osseous defects and method of making same Nonstress-bearing implantable bone prosthesis Partially purified osteogenic factor and process for preparing same from demineralized bone InventorsAssigneeApplicationNo. 312091 filed on 09/28/1994US Classes:514/12, 25 or more peptide repeating units in known peptide chain structure424/85.1, LYMPHOKINE424/422, Implant or insert424/423, Surgical implant or material514/21, Produced by or extracted from animal tissue514/801, COLLAGEN, GELATIN OR DERIVATIVES THEREOF530/351, Lymphokines, e.g., interferons, interlukins, etc.530/356, Collagen530/399, Hormones, e.g., prolactin, thymosin, growth factors, etc.530/840Bones; tendons; teeth; cartilageExaminersPrimary: Tsang, Cecilia J.Assistant: Mohamed, Abdel A. Attorney, Agent or FirmForeign Patent References
International ClassesA61K 038/00C07K 001/00 A61F 002/00 AbstractThe present invention provides improved osteogenic compositions having enhanced by the sorption of growth factors, of nutrient factors, or drugs onto or into the compositions. Compositions may consist of collagen and demineralized bone materials onto and into which growth factors, antimicrobial agent, a nutrient factors, or other soluble factors may be sorbed to enhance the osteogenic factor. These materials can be used in a wide range of clinical procedures to replace and restore osseous or periodontal defects.Field of Search25 or more peptide repeating units in known peptide chain structureProduced by or extracted from animal tissue COLLAGEN, GELATIN OR DERIVATIVES THEREOF LYMPHOKINE Implant or insert Surgical implant or material Lymphokines, e.g., interferons, interlukins, etc. Collagen Hormones, e.g., prolactin, thymosin, growth factors, etc. Bones; tendons; teeth; cartilage |
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