U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Water-based topical cream containing nitroglycerin and method of preparation and use thereof

Patent 5698589 Issued on December 16, 1997. Estimated Expiration Date: Icon_subject January 30, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Transdermal nitroglycerin pad
Patent #: 4336243
Issued on: 06/22/1982
Inventor: Sanvordeker ,   et al.

Treatment of sexual dysfunction
Patent #: 4521421
Issued on: 06/04/1985
Inventor: Foreman

Impotence ointment
Patent #: 4801587
Issued on: 01/31/1989
Inventor: Voss ,   et al.

Aqueous nitroglycerin injection and manufacturing process
Patent #: 5001151
Issued on: 03/19/1991
Inventor: Alam, et al.

Method and composition for treating impotence
Patent #: 5059603
Issued on: 10/22/1991
Inventor: Rubin

Penetration enhancers for transdermal delivery of systemic agents
Patent #: 5204339
Issued on: 04/20/1993
Inventor: Minaskanian, et al.

Urethral insert for treatment of erectile dysfunction
Patent #: 5242391
Issued on: 09/07/1993
Inventor: Place, et al.

Topical compositions and methods for treatment of male impotence Patent #: 5256652
Issued on: 10/26/1993
Inventor: El-Rashidy

Inventor

Assignee

Application

No. 594304 filed on 01/30/1996

US Classes:

514/509(O=)N(=O)-O-C containing (e.g., nitrate ester, etc.)

Examiners

Primary: Jarvis, William R. A.

Attorney, Agent or Firm

International Class

A61K 031/21

Abstract

A stable, uniform, water-based topical cream containing nitroglycerin, a penetration enhancer, water, a thickener and an emulsifier is provided. Also provided are the method of preparing the cream and the use of the cream for treating male erectile dysfunction or female anorgasmia. The present invention also relates to treating patients suffering from microvascular diseases or from injured tissue.

Other References

  • Joy et al., Comparative Pharmacodynamics and Hemodynamics of the Topical Application to the Penis of Nitroglycerin Ointment versus An Aqueous Nitroglycerin Gel in Healthy Male Volunteers, American Urological Association, Inc., 1994 Annual Meeting, San Francisco, CA, 199
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$16.95more info
 
Sign InRegister
Username  
Password   
forgot password?