U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Delivery device having encapsulated excipients

Patent 5697922 Issued on December 16, 1997. Estimated Expiration Date: Icon_subject May 11, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Osmotic system for delivering selected beneficial agents having varying degrees of solubility
Patent #: 4111201
Issued on: 09/05/1978
Inventor: Theeuwes

Osmotic system with means for improving delivery kinetics of system
Patent #: 4111203
Issued on: 09/05/1978
Inventor: Theeuwes

Dispensing device with drug delivery patterns
Patent #: 4608048
Issued on: 08/26/1986
Inventor: Cortese ,   et al.

Dosage form comprising solubility regulating member
Patent #: 4755180
Issued on: 07/05/1988
Inventor: Ayer ,   et al.

Swelling modulated polymeric drug delivery device
Patent #: 5120548
Issued on: 06/09/1992
Inventor: McClelland, et al.

Enteric coated pharmaceutical compositions
Patent #: 5225202
Issued on: 07/06/1993
Inventor: Hodges, et al.

Multiparticulate pulsatile drug delivery system Patent #: 5260068
Issued on: 11/09/1993
Inventor: Chen

Inventor

Application

No. 424476 filed on 05/11/1995

US Classes:

604/892.1, Osmotic or diffusion pumped device or system424/473With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)

Examiners

Primary: Buiz, Michael
Assistant: Nguyen, Hiep T.

Attorney, Agent or Firm

Foreign Patent References

  • 0357369 EP. 03/13/1990

International Class

A61K 009/22

Abstract

An asymmetric membrane, osmotic, delivery device having coated macroparticulate solubility modifiers. The device comprises a beneficial agent, an osmagent, a coated macroparticulate solubility modifier and an asymmetric membrane that surrounds the device components. The device is useful for dispensing a beneficial agent to an aqueous environment of use. The coated macroparticles modify the solubility of the beneficial agent so that it's release can be controlled. The larger size of the solubility modifier macroparticles provides, for example, a longer release duration than would have been possible with a smaller size.

Other References

  • G. A. McClelland et al, "The Solubility-Modulated Osmotic Pump: In vitro/In vivo Release of Diltiazem Hydrochloride", Pharma. Research, vol. 8, No. 1, pp. 88-92 (1991
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$18.95more info
 
Sign InRegister
Username  
Password   
forgot password?