U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method of treating psychosis using azaheterocyclylmethyl

Patent 5696136 Issued on December 9, 1997. Estimated Expiration Date: Icon_subject June 2, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3759927

3826835

3845060

2-Benzoxepins
Patent #: 4153612
Issued on: 05/08/1979
Inventor: McCall

Methods of treating psychosis
Patent #: 4179510
Issued on: 12/18/1979
Inventor: McCall

Neuroleptic n-oxacyclyl-alkylpiperidine derivatives
Patent #: 4470989
Issued on: 09/11/1984
Inventor: Henning ,   et al.

Benzopyran fungicidal compositions and use
Patent #: 4745114
Issued on: 05/17/1988
Inventor: Elliott ,   et al.

Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
Patent #: 4826848
Issued on: 05/02/1989
Inventor: Janssens ,   et al.

Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds
Patent #: 4957928
Issued on: 09/18/1990
Inventor: Frostl, et al.

Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds and compositions
Patent #: 5112855
Issued on: 05/12/1992
Inventor: Frostl, et al.

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Inventors

Application

No. 459071 filed on 06/02/1995

US Classes:

514/322, Plural ring nitrogens in the polycyclo ring system514/278, Spiro ring system514/320, Hetero ring in the polycyclo ring system514/321, Plural hetero atoms in the polycyclo ring system514/323, Ring nitrogen in the polycyclo ring system514/338, Plural hetero atoms in the polycyclo ring system514/339, Ring nitrogen in the polycyclo ring system514/373, Polycyclo ring system having the thiazole ring as one of the cyclos514/375, Polycyclo ring system having the oxazole ring as one of the cyclos514/387, Polycyclo ring system having the diazole ring as one of the cyclos514/414Additional hetero ring which is not part of the bicyclo ring system

Examiners

Primary: Chang, Ceila

Attorney, Agent or Firm

Foreign Patent References

  • 352613 EP. 01/21/1990

International Classes

A61K 031/445
A61K 031/415
A61K 031/40

Foreign Application Priority Data

1991-12-09 DE

Abstract

A method of treating psychosis by administering to a patient an azaheterocyclylmethyl-chroman of the formula: ##STR1## in which E represents an azaheterocyclyl group selected from the group consisting of: ##STR2## wherein R6 represents hydrogen, hydroxyl, halogen or phenyl; andrepresents an integer 0-8;and the other substituents are as defined herein;or an optically isomeric form thereof or a salt thereof.

Other References

  • X references in copending SN 08/460,475
  • Eur. J. Med. Chem. 22 (1987) 539-544
  • Farmaco, Ed. Sci. 42 (11), 805-813 (1987)
  • J. Labelled, Comp., Pharm. 24, 909, 1987
  • Aldrichimica Acta 18, 25, 1985
  • Still et al., J. Org. Chem. 43, 2923, 1978
  • W.U. Dompert et al., Naunyn-Schmiedeberg's Arch. Pharmacol. (1985), 328, 467-470
  • J. Traber et al., TIPS, 8, 432 (1987)
  • M. Ennis, "Current Opinion in Investigational Drugs" (Apr. 1993)
  • Lozonczy et al., Pharmacology: 3rd generation of progress, H.Y. Melzer, p. 715, New York (1987)
  • Athen et al., "Clinical Effects of Moderate and High Doses of Carpipramine", Index Medicus, Abs. No. 013711 (1977
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