Patent 5695743 Issued on December 9, 1997. Estimated Expiration Date: December 9, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
Other References
Dictionnaire Vidal, pp. 1195, 1927, 2238
New Scientist, p. 22, Apr. 23, 1987
American Journal of Hospital Pharmacy, vol. 47, Jun. 1990
Journal of Aerosol Medicine, vol. 4, No. 3, pp. 181-187, 1991
SCRIP No. 1926, p. 30, May 27, 1994
Rompps Chemie-Lexikon, 8th Ed., p. 3898, 1987
Aerosol Age, Jul. 1988, pp. 32-33 and 42-43
Handbook of Aeorsol Technology, 2nd Ed., pp. 30-35, 166-167 and 232-233, 1979
Eur. Respir. J. 1990
Medical Device Technology 5, 21-25, 1991
"CFC-Gasser I Medicinski Spray", Mar. 1989, Pedersen et al., pp. 753-755
"CFC Propellant Substitution: International Perspectives", Pharmaceutical Technology International, 1989, Fischer et al., pp. 16-18
Aerosol Age, Nov. 1989, pp. 6,8
Aerosol Age, Nov. 1989, p. 12
Manufacturing Chemist, Nov. 1989, p. 8
Aerosol Age, Nov. 1989, pp. 16-19
Aerosol Age, Nov. 1989, pp. 24-26
Product Information "Les Substituts F 22 -F 502, FC 142b, F 123 -F 134a, FC 141b", Atochem, dated Oct. 1988
Copy of the product Dexa-Rhinospray sold by C.H. Boehringer Sohn
Physicians' Desk Reference, 40th Edition 1986, Medical Economics Company Inc. at Oradell, NJ "Comparison of Output Particle Size Distributions from Pressurised Aerosols Formulated as Solutions or Suspensions" (R.N. Dalby and P.R. Byron, Pharmaceutical Res., vol. 5, No. 1 (1988) p. 36)
The Theory & Practice of Industrial Pharmacy, Leon Lachman et al., 3rd Ed., Lea & Febiger 1986, Chapter 20, pp. 597, 599 and 603
Chemical and Engineering News, 24 Nov. 1986, p. 52
Dupont Update, Mar. 1987
Manufacturing Chemist, May 1988
HFC 134a as a Substitute Refrigerant for CFC 12, H.O. Spauschus, Paper presented 18 to 21 Jul. 1988
Handbook of Aerosol Technology, Second Edition (1979), pp. 30, 32, and 33
U.S. Senate Hearing, May 12-14, 1987, pp. 487 and 347
The Theory and Practice of Industrial Pharmacy, 2nd Edition, 1976, Lea & Fabiger, Philadelphia, pp. 270 and 276-280
K. Thoma, Aerosol -Moglichkeiten und Probleme einer Darreichungsform, Werbe-und Vertriebsgesellschaft Deutscher Apotheker m.b.H., Frankfurt a.M., 1979, Seiten 153-161 (with translation)
December 9, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
