Did You Know...
...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.
PatentStorm News
Make the Most of PatentStorm
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest patents by subscribing to an RSS feed.
Got questions? Ask a Patent Expert!
Registered users: Manage your profile, comments and alerts.
US Patent 5689052 - Synthetic DNA sequences having enhanced expression in monocotyledonous plants and method for preparation thereof
Estimated Patent Expiration Date:
September 19, 2015Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractA method for modifying a foreign nucleotide sequence for enhanced accumulation of its protein product in a monocotyledonous plant and/or increasing the frequency of obtaining transgenic monocotyledonous plants which accumulate useful amounts of a transgenic protein by reducing the frequency of the rare and semi-rare monocotyledonous codons in the foreign gene and replacing them with more preferred monocotyledonous codons is disclosed. In addition, a method for enhancing the accumulation of a polypeptide encoded by a nucleotide sequence in a monocotyledonous plant and/or increasing the frequency of obtaining transgenic monocotyledonous plants which accumulate useful amounts of a transgenic protein by analyzing the coding sequence in successive six nucleotide fragments and altering the sequence based on the frequency of appearance of the six-mers as to the frequency of appearance of the rarest 284, 484, and 664 six-mers in monocotyledonous plants is provided. Also disclosed are novel structural genes which encode insecticidal proteins of B. t. k. and monocotyledonous (e.g. maize) plants containing such novel structural genes.Other References
| InventorsApplicationNo. 530492 filed on 09/19/1995US Classes:800/302, Insect resistant plant which is transgenic or mutant536/23.71Bacillus thuringiensis insect toxinField of Search435/69.8, Signal sequence (e.g., beta-galactosidase, etc.)435/69.7, Fusion proteins or polypeptides536/23.1, DNA or RNA fragments or modified forms thereof (e.g., genes, etc.)536/23.71, Bacillus thuringiensis insect toxin530/350PROTEINS, I.E., MORE THAN 100 AMINO ACID RESIDUESExaminersPrimary: Benzion, GaryAttorney, Agent or FirmUS Patent References5082767Codon pair utilizationIssued on: 01/21/1992 Inventor: Hatfield, et al. Foreign Patent References
International ClassesA01H 005/00C12N 015/11 C12N 015/82 |
