Patent ReferencesProcess for the preparation of a mixture of an anti-inflammatory steroid and a fluoro-chloro-hydrocarbon to be used as a propellant Physically modified beclomethasone dipropionate suitable for use in aerosols Micronised beclomethasone dipropionate monohydrate compositions and methods of use Patent #: 4866051 InventorsAssigneeApplicationNo. 458241 filed on 06/02/1995US Classes:514/180, 9-position substituted424/45Organic pressurized fluidExaminersPrimary: Cintins, Marianne M.Assistant: Jones, Dwayne C. Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/56A61L 009/04 Foreign Application Priority Data1992-02-06 GBAbstractThis invention relates to aerosol formulations of use for the administration of medicaments by inhalation, in particular a pharmaceutical aerosol formulation which comprises: (a) beclomethasone dipropionate monohydrate, the particle size of substantially all the monohydrate being less than 20 microns; (b) at least 0.015% by weight of the formulation of water in addition to the water of crystallization associated with the monohydrate; and (c) a fluorocarbon or hydrogen-containing chlorofluorocarbon propellant. A method of treating respiratory disorders which comprises administration by inhalation of an effective amount of a pharmaceutical aerosol formulation as defined is also described. | |