U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Medicinal aerosol formulations

Patent 5683677 Issued on November 4, 1997. Estimated Expiration Date: Icon_subject May 31, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2868691

2885427

3014844

3219533

3261748

3608066

3897779

Aerosol composition
Patent #: 4083954
Issued on: 04/11/1978
Inventor: Tsuchiya, et al.

Manufacture of halogenated compounds
Patent #: 4129603
Issued on: 12/12/1978
Inventor: Bell

Composition for treating airway disease
Patent #: 4161516
Issued on: 07/17/1979
Inventor: Bell

More ...

Inventors

Assignee

Application

No. 455012 filed on 05/31/1995

US Classes:

424/45, Organic pressurized fluid424/43, EFFERVESCENT OR PRESSURIZED FLUID CONTAINING424/44, Gas produced in situ by chemical reaction424/46Powder or dust containing

Examiners

Primary: Page, Thurman K.
Assistant: Benston, William E. Jr.

Attorney, Agent or Firm

Foreign Patent References

  • 79051/94 AU. 05/12/1995
  • 275404 EP. 07/12/1988
  • 518601 EP. 12/12/1992
  • 1719443 DE. 04/12/1973
  • 2736500 DE. 02/12/1978
  • 2737132 DE. 02/12/1978
  • 52-80282 JP. 05/12/1977
  • 837465 GB. 06/12/1960
  • 2046093 GB. 11/12/1980
  • 90/07333 WO. 07/12/1990
  • 91/04011 WO. 04/12/1991
  • 91/11495 WO. 08/12/1991
  • 92/00061 WO. 01/12/1992
  • 92/22287 WO. 12/12/1992
  • 93/11743 WO. 06/12/1993
  • 93/11745 WO. 06/12/1993
  • 93/11744 WO. 06/12/1993

International Class

A61L 009/04

Foreign Application Priority Data

1988-12-06 GB

Abstract

A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.

Other References

  • Physicians' Desk Reference, 40th Edition 1986, Medical Economics Company Inc. at Oradell, NJ
  • "Comparison of Output Particle Size Distributions from Pressurised Aerosols Formulated as Solutions or Suspensions", R.N. Dalby and P.R. Byron, Pharmaceutical Res., vol. 5, No. 1 (1988), p. 36
  • The Theory & Practice of Industrial Pharmacy, Leon Lachman et al., 3rd Ed., Lea & Febiger 1986, Chapter 20, pp. 597, 599 and 603
  • Chemical and Engineering News, 24 Nov. 1986, p. 52
  • Dupont Update, Mar. 1987
  • Manufacturing Chemist, May 1988
  • HFC 134a as a Substitute Refrigerant for CFC 12, H.O. Spauschus, Paper presented 18 to 21 Jul. 1988
  • Handbook of Aerosol Technology, Second Edition (1979), pp. 30, 32 and 33
  • Product Information "Les Substituts F 22--F 502, FC 142b, F 123--F 134a, FC 141b", Atochem, dated Oct. 1988
  • Dictionnaire Vidal (1979), pp. 392--Chibro-Plast-, 1926--Spray 1000--and 2239-2240--Ventoline Aerosol-doseur
  • F. Dorvalut "L'Officine" (1978), pp. 547-548
  • Copy of the product Dexa-Rhinospray sold by C.H. Boehringer Sohn
  • U.S. Senate Hearing, May 12-14, 1987, pp. 487 and 347
  • The Theory and Practice of Industrial Pharmacy, 2nd Edition, 1976, Lea & Fabiger, Philadelphia, pp. 270 and 276-280
  • "CFC-Gasser I Medicinske Spray", Mar. 1989, Pedersen et al., pp. 753-755
  • "CFC Propellant Substitution: International Perspectives", Pharmaceutical Technology International, 1989, Fischer et al., pp. 16-18
  • Aerosol Age, Nov. 1989, pp. 6,8
  • Aerosol Age, Nov. 1989, p. 12
  • Manufacturing Chemist, Nov. 1989, p. 8
  • Aerosol Age, Nov. 1989, pp. 16-19
  • Aerosol Age, Nov. 1989, pp. 24-26
  • International Journal of Refrigeration, 1988, 11,389 (Spauschus, Nov. 1988)
  • Manufacturing Chemist, Feb. 1988, p. 9
  • Processing, Dec. 1988, p. 7
  • "Fluorocarbons and Ozone", Apr. 1988
  • Manufacturing Chemist, Sep. 1988, p. 9
  • Manufacturing Chemist, Jun. 1988, p. 3
  • Aerosol Age, Jul. 1988, pp. 28-31
  • New Scientist, 26 May 1988, pp. 56-60
  • Western Union "Mailgram", DuPont, Mar. 24, 1988
  • Aerosol Age, Aug. 1988, pp. 32-39
  • Research Disclosure, vol. 162, 1977, p. 70 (#16265)
  • Dictionnaire Vidal, pp. 1195, 1927, 2238
  • New Scientist, p. 22, Apr. 23, 1987
  • American Journal of Hospital Pharmacy, vol. 47, Jun. 1990
  • Journal of Aerosol Medicine, vol. 4, No. 3, pp. 181-187, 1991
  • SCRIP No. 1926, p. 30, May 27, 1994
  • Rompps Chemie-Lexikon, 8th Ed., p. 3898, 1987
  • Aerosol Age, Jul. 1988, pp. 32-33 and 42-43
  • Handbook of Aerosol Technology, 2nd Ed., pp. 30-35, 166-167 and 232-233, 1979
  • Eur. Respir. J. 1990
  • Medical Device Technology 5, 21-25, 1991
  • K. Thoma, Aerosol--Moglichkeiten und Probleme einer Darreichungsforom, Werbe-und Vertriebsgesellschaft Deutscher Apotheker m.b.H., Frankfurt a.M., 1979, Seiten 153-161 (with translation)
  • K. Thoma, Pharma Technologie, Concept Heidelberg, 1984, Seiten 94-102 (translation to follow)
  • H-FCKW 123 und H-FKW 134a, Frigen-Information KT 08/88 (with translation)
  • T. Nelson, Alternative Formulations to Reduce CFC Use in U.S. Exempted and Excluded Aerosol Products, Report No. EPA-600/2-89-061; Nov. 198
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