Bioactive load bearing bone graft compositions

Patent 5681872 Issued on October 28, 1997. Estimated Expiration Date:

December 7, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

2920971

3629187

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Inventor

Erbe, Erik M.

Assignee

Orthovita, Inc.

Application

No. 568812 filed on 12/07/1995

US Classes:

523/114, Composition which anchors by ingrowth of surrounding tissue106/35, Dental106/634, Organic material containing106/691, Specified filler or organic material containing260/998.11, DENTAL501/70, Calcium oxide containing523/113, Composition suitable for use as tissue or body member replacement, restorative, or implant523/115, Composition suitable for use as tooth or bone replacement, restorative, or implant524/414, Phosphorus atom DNRM524/456Group IIA metal atom DNRM

Examiners

Primary: Merriam, Andrew E. C.

Attorney, Agent or Firm

Woodcock Washburn Kurtz Mackiewicz & Norris LLP

Foreign Patent References

2208236 DE. 02/13/1972
62-010939 JP. 02/13/1987
WO 93/16738 WO. 09/13/1993

International Classes

A61K 006/06
C08K 003/40

Abstract

Novel fillers comprising combeite glass-ceramic are provided. hardenable restorative compositions comprising particulate combeite glass-ceramic provide improved biocompatibility in bone restorations. Hard, shaped bodies for orthopaedic, dental and other uses are also provided.

Other References

W.F. Brown Solubilities of Phosphate & Other Sparingly Soluble Compounds Environmental Phosphorous Handbook, Ch. 10 1973
Vuillemin et al. Fixationof Bone Fragments with BIOCHEM Arch. Otolygol. Head Neck Surg. 1987 113:836-840
Saito et al. Experimental Studies on a new bioactive bone cement; hydroxyapatite composite resin Biomaterials 1994 15:156-160
Zamora et al. abstract Spring 1995 meeting of the American Chemical Society Bioglass Reinforced Dental Composites: Thermal Mechanical Properties (1995)
Tamura et al. Bioactive bone cement: The effect of amounts of glass powder and histologic changes with time Journal of Biomedical Materials Research 1995 29:551-559
Dickens-Venz et al. Physical and Chemical properties of resin-reinforced calcium phosphate cements Dent. Mater. 1994 10:100-106
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Sahama et al Gozenite and comeite, two new silicates from the Belgian Congo Mineral. Mag. 1957 31:503-511
Introduction to Ceramics 2nd Ed., p. 528, John Wiley & Sons 1976 W.D. Kangery
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