U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Antibacterial compositions

Patent 5679336 Issued on October 21, 1997. Estimated Expiration Date: Icon_subject October 18, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Piperazinyl derivatives of quinoline carboxylic acids
Patent #: 4146719
Issued on: 03/27/1979
Inventor: Irikura

1,4-Dihydro-quinoline-3-carboxylic acid derivatives, process for their preparation and compositions containing them
Patent #: 4292317
Issued on: 09/29/1981
Inventor: Pesson

Benzoxazine derivatives
Patent #: 4382892
Issued on: 05/10/1983
Inventor: Hayakawa ,   et al.

Disinfectant solution for contact lens
Patent #: 4615882
Issued on: 10/07/1986
Inventor: Stockel

7-amino-1-cyclopropyl-4-oxo-1, 4-dihydro-quinoline-and naphthyridine-3-carboxylic acids and antibacterial agents containing these compounds Patent #: 4670444
Issued on: 06/02/1987
Inventor: Grohe ,   et al.

Inventors

Application

No. 544624 filed on 10/18/1995

US Classes:

424/78.04, Ophthalmic preparation514/253.08, Having -C(=X)-, wherein X is chalcogen, bonded directly to carbon of the hetero ring of the quinoline ring system514/912OPHTHALMIC

Examiners

Primary: Fay, Zohreh

Attorney, Agent or Firm

International Class

A61K 031/74

Abstract

Aqueous pharmaceutical compositions containing a synergistic combination of a quinolone and a polystyrene sulfonic acid polymer are described, wherein the compositions are clear solutions which are comfortable and have sustained release. Methods for use of the compositions are also disclosed. This type of formulation is particularly useful with ciprofloxacin-type quinolones by greatly increasing the solubility of these quinolones, making it feasible to have aqueous solutions containing such quinolones at or near physiological pH.

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