Treating urinary incontinence using (S)-desethyloxybutynin
Patent 5677346 Issued on October 14, 1997. Estimated Expiration Date: 
June 7, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 7, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorsAssigneeApplicationNo. 480194 filed on 06/07/1995US Classes:514/617, R contains benzene ring424/449, Transdermal or percutaneous424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/464, Tablets, lozenges, or pills514/310, Nitrogen, other than as nitro or nitroso, attached directly to the isoquinoline ring system by nonionic bonding514/946PENETRANT OR ABSORBENT (ENHANCES PENETRATION INTO SUBJECT TREATED)ExaminersPrimary: Rollins, John W.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/165A61K 009/70 AbstractA method for treating urinary incontinence while avoiding concomitant liability of adverse effects associated with racemic oxybutynin is disclosed. The method comprises administering a therapeutically effective amount of (S)-oxybutynin, (S)-desethyloxybutynin or a pharmaceutically acceptable salt thereof, substantially free of the corresponding R enantiomer. Pharmaceutical compositions in the form of tablets and transdermal devices comprising (S)-oxybutynin or (S)-desethyloxybutynin and an acceptable carrier are also disclosed, as is a synthesis of desethyloxybutynin.Other References
Field of SearchR contains benzene ringNitrogen, other than as nitro or nitroso, attached directly to the isoquinoline ring system by nonionic bonding PENETRANT OR ABSORBENT (ENHANCES PENETRATION INTO SUBJECT TREATED) Transdermal or percutaneous Capsules (e.g., of gelatin, of chocolate, etc.) Tablets, lozenges, or pills | |
