U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Combination of a bronchodilator and a steroidal anti-inflammatory drug for the treatment of respiratory disorders

Patent 5674860 Issued on October 7, 1997. Estimated Expiration Date: Icon_subject October 7, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Compositions and method of treating with stereoisomeric mixtures of 2-unsymmetrical 16,17-methylenedioxy steroids
Patent #: 3983233
Issued on: 09/28/1976
Inventor: Brattsand ,   et al.

଱-Aminomethylbenzyl alcohol derivatives Patent #: 3994974
Issued on: 11/30/1976
Inventor: Murakami ,   et al.

Inventors

Assignee

Application

No. 317407 filed on 10/03/1994

US Classes:

514/171, With additional active ingredient514/174, -O-C-O- is part of a hetero ring (e.g., acetonide, etc.)514/653, Hydroxy, bonded directly to carbon, attached directly or indirectly to the acyclic carbon or chain by acyclic nonionic bonding (e.g., beta hydroxy phenethylamines, etc.)514/826ASTHMA

Examiners

Primary: Henley, III, Raymond

Attorney, Agent or Firm

Foreign Patent References

  • 0416951 EP. 03/13/1991
  • 0416950 EP. 03/13/1991

International Classes

A61K 031/56
A61K 031/135

Foreign Application Priority Data

1991-12-18 EP

Abstract

Effective amounts of formoterol and/or a physiologically acceptable salt and/or solvate thereof and budesonide are used in combination for simultaneous, sequential or separate administration by inhalation in the treatment of an inflammatory respiratory disorder, such as asthma.

Other References

  • Marsac, et al., Annals of Allergy 63, 220-224 (1989)
  • Maesen, et al., Chest 97, 590-594 (1990)
  • McDonald, et al., Current Medical Research and Opinion 11, 116-122 (1988)
  • Bond, New Zealand Medical Journal, p. 369, Aug. 28, 1991
  • Dahl, et al., J. Allergy Clin. Immunol. 83, 811-815 (1989)
  • Dal Negro, et al., Current Therapeutic Research 35, 561-565 (1984)
  • Wallin, et al., Thorax 45, 259-261 (1990)
  • Lorentzen, et al., Thorax 45, 733-735 (1990)
  • Ebden, et al., Thorax 41, 869-874 (1986)
  • Morris, et al., J. Allergy Clin. Immunol. 75, 1-14 (1985)
  • Holst, et al., New Zealand Medical Journal 79, 769-773 (1974)
  • Morris, et al., Chest 88, 133S-141S (1985)
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  • Lurie, et al., Lung Suppl., 154-167 (1990)
  • Paterson, et al., Am. Rev. Resp. Dis. 120, 1149-1188 (1979)
  • O'Loughlin, Postgraduate Medicine 82, 231-238 (1987)
  • Stafford, Postgraduate Medicine 84, 85-98 (1988)
  • Lacronique, et al., Rev. Mal. Resp. 6, 15-30 (1989)
  • Quaglia, et al., Folia Allergol. Immunol. Clin, 24, 318-327 (1977)
  • Jean H. Marsac, "Inhaled beta agonists and inhaled steroids in the treat. of asthma", Ann. of Allergy, 63(3), Sep. 1989, pp. 220-224
  • Nils Svedmyr, "The current place of beta agonists in the mngmt. of asthma", Lung (USA), 168 no. supp, 1990, NY pp. 105-11
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