U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Canisters containing aerosol formulations containing P134a and fluticasone propionate

Patent 5674472 Issued on October 7, 1997. Estimated Expiration Date: Icon_subject May 19, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2868691

2885427

3014844

3219533

3320125

3809294

3897779

Steroidal aerosol compositions and process for the preparation thereof
Patent #: 4044126
Issued on: 08/23/1977
Inventor: Cook, et al.

Aerosol propellant compositions
Patent #: 4174295
Issued on: 11/13/1979
Inventor: Bargigia ,   et al.

Process for the preparation of a mixture of an anti-inflammatory steroid and a fluoro-chloro-hydrocarbon to be used as a propellant
Patent #: 4347236
Issued on: 08/31/1982
Inventor: Tanskanen

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Inventors

Assignee

Application

No. 444919 filed on 05/19/1995

US Classes:

424/45, Organic pressurized fluid222/635, Pressurized aerosol container424/46Powder or dust containing

Examiners

Primary: Bawa, Raj

Attorney, Agent or Firm

Foreign Patent References

  • 134923 DK. 02/13/1977
  • 0 372 777 EP. 06/13/1990
  • 0 504 112 EP. 09/13/1992
  • 27 03 119 DE. 10/13/1990
  • 437766 SE. 03/13/1985
  • 86/04233 WO. 07/13/1986
  • 90/07333 WO. 07/13/1990
  • 91/04011 WO. 04/13/1991
  • 91/11496 WO. 08/13/1991
  • 91/11495 WO. 08/13/1991
  • 91/11173 WO. 08/13/1991
  • 91/14422 WO. 10/13/1991
  • 92/00107 WO. 01/13/1992
  • 92/06675 WO. 04/13/1992
  • 92/08447 WO. 05/13/1992
  • 92/08446 WO. 05/13/1992
  • 92/11190 WO. 07/13/1992
  • 92/22287 WO. 12/13/1992
  • 92/22288 WO. 12/13/1992
  • 93/11745 WO. 06/13/1993
  • 93/11743 WO. 06/13/1993
  • 93/11744 WO. 06/13/1993
  • 93/11747 WO. 06/13/1993

International Class

A61K 009/12

Foreign Application Priority Data

1991-12-12 GB

Abstract

The present invention relates to canisters suitable for delivering a pharmaceutical aerosol formulation which comprises a container capable of withstanding the vapor pressure of the propellant used, which container is closed with a metering valve and contains a pharmaceutical aerosol formulation consisting essentially of a particulate medicament which is fluticasone propionate or a physiologically acceptable solvate thereof and 1,1,1,2-tetrafluoroethane as propellant, which formulation contains less than 0.0001% w/w surfactant based on the weight of the medicament, the particulate medicament being present in an amount from 0.005% to 5% w/w relative to the total weight of the formulation and having a particle size of less than 100 microns. A further particulate medicament may also be present in the pharmaceutical aerosol formulation.

Other References

  • Gennaro, A.R. (1985). Remington's Pharmaceutical Sciences (17th ed.). Mack Pub. Co., pp. 1670-1677
  • Oberholz, Frankfurter, Allgemeine Zeitung, 1989, vol. 25, No. 207, p. 7
  • Dalby et al., Pharmaceutical Technology, 1990, vol. 14, No. 3, pp. 28-33
  • Arnzacort™ Carton, William H. Rorer, Inc., Fort Washington, Pennsylvania, USA 19034, 1986
  • Pharmaceutical Journal, 1990, vol. 245, pp. 428-429
  • The Theory and Practice of Industrial Pharmacy, 2nd Ed., 1978 (Philadelphia, PA: Lee and Febiger), pp. 270 and 276-278
  • Handbook of Aerosol Technology, 2nd Edition, 1979 (New York, New York: Van Nostrand Reinhold Company), pp. 30, 32, 33, 166, 167, 232, 233
  • U.S. Senate Hearings, 12-14 May 1987, 343-347, 437 (U.S. Government Printing Office, Washington, D.C., 1987), CIS:1987-S321-26
  • Hagers Handbook of Pharmaceutical Practice, 1971, pp. 342-354 (Berlin: Springer-Verlag
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