Aerosol formulations containing P134a and salbutamol
Patent 5674471 Issued on October 7, 1997. Estimated Expiration Date: 
May 19, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 19, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2868691 2885427 3014844 3219533 3320125 3809294 3897779 Steroidal aerosol compositions and process for the preparation thereof Aerosol propellant compositions Process for the preparation of a mixture of an anti-inflammatory steroid and a fluoro-chloro-hydrocarbon to be used as a propellant InventorsAssigneeApplicationNo. 444725 filed on 05/19/1995US Classes:424/45, Organic pressurized fluid424/46, Powder or dust containing514/826ASTHMAExaminersPrimary: Bawa, RajAttorney, Agent or FirmForeign Patent References
International ClassA61K 009/12Foreign Application Priority Data1991-12-12 GBAbstractThe invention relates to a pharmaceutical aerosol formulation consisting essentially of particulate medicament which is salbutamol or a physiologically acceptable salt or solvate thereof and 1,1,1,2-tetrafluoroethane as propellant, which formulation contains less than 0.0001% surfactant based upon the weight of medicament, particulate medicament being present in an amount of 0.005% to 5% w/w relative to the total weight of the formulation and having a particle size of less than 100 microns, with the provisos that when said formulation consists of salbutamol and 1,1,1,2-tetrafluoroethane in a weight ratio of 0.05:18, said salbutamol is present in the form of a physiologically acceptable salt and when said formulation consists of salbutamol or salbutamol sulphate and 1,1,1,2-tetrafluoroethane the weight to weight ratio of medicament to propellant is other than 69:7900 or 0.866%.Other References
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