Multicompartment hard capsule with control release properties
Patent 5672359 Issued on September 30, 1997. Estimated Expiration Date: 
November 20, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 20, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2451022 3122475 3197369 3415249 3814809 Sustained release composition Sustained-release formulation and production thereof Slow release formulation Multi-layer granule Multi-unit delivery system InventorsAssigneeApplicationNo. 560946 filed on 11/20/1995US Classes:424/463, Coated capsules424/408, Capsule or pelleted or tablet424/452, With claimed designated perfecting feature in contents (e.g., excipient, lubricant, etc.)424/453, Telescoping two piece424/454, With tamperproof, locking, or sealing feature424/455, Containing emulsions, dispersions, or solutions424/456GelatinExaminersPrimary: Levy, Neil S.Attorney, Agent or FirmForeign Patent References
International ClassA61K 009/52AbstractThe present invention relates to a hard capsule made from a material such as gelatin, starch or a hydrophilic polymer. The capsule of the present invention is formulated into a delivery system which incorporates pharmacologically active components in three or more distinct compartments. When three compartments are utilized in the capsule, the outer compartment incorporates a drug and excipients into a layer which coats the outer part of the capsule. This layer represents the rapid release portion of the delivery system. The intermediate compartment comprises a powder formulation comprised of a drug and excipients which represents the intermediary speed release portion of the delivery system. The innermost compartment incorporates the active ingredient or ingredients in a multiparticulate form, such as small pellets, and represents the slow release component of the delivery system.Other References
Field of SearchCapsule or pelleted or tabletDepot, pellet, matrix, or suppository Anal, rectal (e.g., suppositories, etc.) Specially adapted for ruminant animal Coated particulate form (e.g., liposome, etc.) With claimed designated perfecting feature in contents (e.g., excipient, lubricant, etc.) Gelatin Sustained or differential release Containing discrete coated particles pellets, granules, or beads Organic coatings Containing proteins or derivatives thereof (e.g., gelatin, etc.) Containing polysaccharide (e.g., cellulose sugars, etc.) Containing solid synthetic polymers Coated capsules Cellulose derivatives Contains waxes, higher fatty acids, higher fatty alcohols CAPSULE (E.G., GELATIN, ETC.) Discrete particles in supporting matrix VAGINAL | |
