Solid fat nanoemulsions
Patent 5662932 Issued on September 2, 1997. Estimated Expiration Date: 
August 27, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
August 27, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPharmaceutical microemulsions Emulsions Lipsopheres for controlled delivery of substances Salt film encapsulated perfluorocarbons Method to reduce particle size growth during lyophilization Red blood cell surrogate Ophthalmic product Solid fat nanoemulsions as drug delivery vehicles Patent #: 5576016 InventorsAssigneeApplicationNo. 697704 filed on 08/27/1996US Classes:424/450, Liposomes424/45, Organic pressurized fluid424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/490, Coated (e.g., microcapsules)424/502, Contains waxes, higher fatty acids, higher fatty alcohols428/402.2, Microcapsule with fluid core (includes liposome)514/937DISPERSION OR EMULSIONExaminersPrimary: Kishore, Gollamudi S.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 009/127A61K 009/16 AbstractThe present invention provides pharmaceutical compositions comprising nanoemulsions of particles comprising a lipid core which is in a solid or liquid crystalline phase at 25° C., stabilized by at least one phospholipid envelope, for the parenteral, oral, intranasal, rectal, or topical delivery of both fat-soluble and water-soluble drugs. Particles have a mean diameter in the range of 10 to 250 nm. A wide variety of drugs and oxygen transporting perfluorocarbons may be encapsulated in the particles. In addition to drug delivery vehicles, the invention provides oxygen transporting blood substitutes, and nanoemulsions for extracorporeal maintenance of tissues prior to transplantation.Other References
Field of SearchLiposomesParticulate form (e.g., powders, granules, beads, microcapsules, and pellets) Coated (e.g., microcapsules) Containing solid synthetic polymers Organic pressurized fluid Contains waxes, higher fatty acids, higher fatty alcohols DISPERSION OR EMULSION Oil-water type Mineral oil-water type Quick break type Polyoxyalkylated compound containing Organic sulfonate, sulfate or sulfite containing Higher fatty acid or derivative containing Microcapsule with fluid core (includes liposome) | |
