Patent 5658742 Issued on August 19, 1997. Estimated Expiration Date: March 15, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
435/7.9, Assay in which an enzyme present is a label435/7.21, Animal cell435/7.23, Tumor cell or cancer cell435/330, Immunoglobulin or antibody binds an expression product of a cancer related gene or fragment thereof (e.g., oncogene, proto-oncogene, etc.)435/331, Immunoglobulin or antibody binds a specifically identified amino acid sequence436/63, BIOLOGICAL CELLULAR MATERIAL TESTED436/64, CANCER530/387.7, Binds expression product of cancer-related gene or fragment thereof (e.g., oncogene, proto-oncogene, etc.)530/387.9, Binds specifically-identified amino acid sequence530/388.2, Binds microorganism or normal or mutant component or product thereof (e.g., animal cell, cell-surface antigen, secretory product, etc.)530/388.8Binds cancer cell or component or product thereof (e.g., cell-surface antigen, etc.)
This invention relates to a monoclonal antibody having affinity to human TCF-II without any affinity to HGF and determination or purification methods of TCF-II using the antibody. The monoclonal antibody can be obtained by adding a blocking solution containing a surface active agent to the culture medium containing monoclonal antibody to block antibodies other than said monoclonal antibody, followed by reaction with a solid phase antigen, TCF-II. Human TCF-II can be selectively and effectively purified or determined without any influence of the presence of HGF by using the antibody.
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