Spectrophotometric method and apparatus for the non-invasive
Blocker device for eliminating specular reflectance from a diffuse reflection spectrum
Non-invasive near infrared measurement of blood analyte concentrations
Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids
Optical system and method for sample analyzation
Non-invasive measurement of blood glucose
Non-invasive determination of glucose concentration in body of patients
Infrared glucose sensor
Non-invasive near-infrared quantitative measurement instrument
System for measuring the saturation of at least one gas, particularly the oxygen saturation of blood
ApplicationNo. 512940 filed on 08/09/1995
US Classes:600/366, Equilibration and analysis of fluid356/39BLOOD ANALYSIS
ExaminersPrimary: Cohen, Lee S.
Assistant: Winakur, Eric F.
Attorney, Agent or Firm
International ClassA61B 005/00
AbstractA method for non-invasively measuring the concentration of an analyte, particularly blood analyte in blood. The method utilizes spectrographic techniques in conjunction with an improved optical interface between a sensor probe and a skin surface or tissue surface of the body containing the blood to be analyzed. An index-matching medium is disclosed to improve the interface between the sensor probe and skin surface during spectrographic analysis. In a preferred embodiment, the blood analyte concentration in blood is quantified utilizing a partial squares analysis relative to a model incorporating analysis of plural known blood samples.