Optical and electrical methods and apparatus for molecule detection
Patent 5653939 Issued on August 5, 1997. Estimated Expiration Date: August 7, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
422/50, ANALYZER, STRUCTURED INDICATOR, OR MANIPULATIVE LABORATORY DEVICE204/456, Gel electrophoresis422/68.1, Means for analyzing liquid or solid sample422/76, Conductiometric type422/82.01, Measuring electrical property422/82.02, Resistance or conductivity422/82.05, Measuring optical property by using ultraviolet, infrared, or visible light422/91, With photometric detector435/5, Involving virus or bacteriophage435/6, Involving nucleic acid435/7.1, Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay435/7.9, Assay in which an enzyme present is a label435/285.2, With means for applying an electric current or charge (e.g., electrofusion, electroporation, etc.)436/149, MEASUREMENT OF ELECTRICAL OR MAGNETIC PROPERTY OR THERMAL CONDUCTIVITY436/150, Of a liquid436/806, ELECTRICAL PROPERTY OR MAGNETIC PROPERTY436/807, APPARATUS INCLUDED IN PROCESS CLAIM (E.G., PHYSICAL SUPPORT STRUCTURES, ETC.)530/300, PEPTIDES OF 3 TO 100 AMINO ACID RESIDUES530/333, Synthesis of peptides530/350PROTEINS, I.E., MORE THAN 100 AMINO ACID RESIDUES
A method and apparatus are disclosed for identifying molecular structures within a sample substance using a monolithic array of test sites formed on a substrate upon which the sample substance is applied. Each test site includes probes formed therein to bond with a predetermined target molecular structure or structures. A signal is applied to the test sites and certain electrical, mechanical and/or optical properties of the test sites are detected to determine which probes have bonded to an associated target molecular structure.
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August 7, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
