U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same

Patent 5648100 Issued on July 15, 1997. Estimated Expiration Date: Icon_subject June 6, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3797485

Anti-cancer device
Patent #: 4536387
Issued on: 08/20/1985
Inventor: Sakamoto ,   et al.

Polyacrolein microspheres
Patent #: 4622362
Issued on: 11/11/1986
Inventor: Rembaum

Sustained release pharmaceutical plaster
Patent #: 4801458
Issued on: 01/31/1989
Inventor: Hidaka ,   et al.

Sustained release pharmaceutical preparation Patent #: 4990340
Issued on: 02/05/1991
Inventor: Hidaka, et al.

Inventors

Assignee

Application

No. 471303 filed on 06/06/1995

US Classes:

424/501, Contains solid synthetic resin424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/491, Containing proteins and derivatives424/492, Gelatin424/496, Containing natural gums/resins424/497, Containing solid synthetic polymers424/500Contains natural gums and resins

Examiners

Primary: Azpuru, Carlos

Attorney, Agent or Firm

International Classes

A61K 009/14
A61K 009/16
A61K 009/50

Foreign Application Priority Data

1991-05-29 FR

Abstract

The present invention concerns the use of microspheres for therapeutic embolization consisting of a hydrophilic acrylic copolymer coated with a cell adhesion promoter.

Other References

  • "Microcarrier Culture of Fibroblastic Cells on Modified Trisacryl Beads", Obrenovitch et al, Biol. Cell (1982), 46,249-256
  • "Polyacrylamide Derivatives to the Service of Bioseparations", Boschetti, J of Biochem. & Biophys. Methods, 19(1989) 21-36
  • "Synthesis and Copolym. of New Water-solulde Polyiodiuated Acrylic Monomers", Brown et al, Makromiol. Chem., Rapid Commun. 6,503-507 (1985)
  • Laurent et al., "Etude Histologique de Plusieurs Materiaux D'Embolisation et d'un Nouveau Type de Materiel Spherique et Adhesif," Innovation et Technologie en Biologie et Medecine 10(3): 357-366 (1989)
  • Mazza et al., "Polymer Design in Dye Chromatography: From the definition of monomers to the evaluation of polymeric supports,"in Protein-Dye Interactions: Developments and Applications, Vijayalaksnmi M.A. ed., Elsevier Appl. Sciences, Elsevier Sci. Publ. Ltd., pp. 126-136 (1989
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