U.S. patents available from 1976 to present.
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System and method for noninvasive detection of arterial stenosis

Patent 5638823 Issued on June 17, 1997. Estimated Expiration Date: Icon_subject August 28, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Dynamic spectral phonocardiograph
Patent #: 4967760
Issued on: 11/06/1990
Inventor: Bennett, Jr., et al.

Noninvasive diagnostic system for coronary artery disease
Patent #: 5036857
Issued on: 08/06/1991
Inventor: Semmlow, et al.

Intelligent stethoscope
Patent #: 5218969
Issued on: 06/15/1993
Inventor: Bredesen, et al.

Risk management system for use with cardiac patients Patent #: 5276612
Issued on: 01/04/1994
Inventor: Selker

Inventors

Assignee

Application

No. 520236 filed on 08/28/1995

US Classes:

600/528, Detecting heart sound600/501, Waveform graph-type pulse recorder600/526Blood output per beat or time interval

Examiners

Primary: Nasser, Robert L.

Attorney, Agent or Firm

International Class

A61B 005/00

Abstract

A system and method for noninvasively detecting coronary artery disease. The system and method utilize a vasodilator drug to increase the signal-to-noise ratio of an acoustic signal that represents diastolic heart sounds of a patient. A wavelet transform is performed on the acoustic signal to provide parameters for a feature vector. Scaled clinical examination parameters such as a patient's sex, age, body weight, smoking condition, blood pressure, and family history are also included in the feature vector. The feature vector is used as an input pattern to neural networks. The output of the neural networks represent a diagnosis of coronary stenosis in a patient.

Other References

  • M. Akay et al., "Acoustical Detection of Coronary Occlusions Using Neural Networks", Nov. 1993, J. Biomed. Eng., pp. 469-473
  • M. Akay et al., "Investigating the Effects of Vasodilator Drugs on the Turbulent Sound Caused by Femoral Artery Stenosis Using Short-Term Fourier and Wavelet Transform Methods", Oct. 1994, IEEE Transactions, vol. 41, pp. 921-928
  • M. Akay, "Noninvasive Diagnosis of Coronary Artery Disease Using a Neural Network Algorithm", (1992), Biological Cybernetics, pp. 361-367
  • S. Mallat et al., "Characterization of Signals from Multiscale Edges", Jul. 1992, IEEE Transactionson Pattern Analysis and Machine Intelligence, vol. 14, pp. 710-73
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