Method for treating diseases mediated by proteases
Patent 5637616 Issued on June 10, 1997. Estimated Expiration Date: June 10, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
514/562, Sulfur nonionically bonded514/28, The hetero ring has 8 or more ring carbons514/29, The hetero ring has exactly 13 ring carbons (e.g., erythromycin, etc.)514/30, The hetero ring has exactly 15 ring carbons514/251, Isoalloxazine (e.g., riboflavins, Vitamin B2, etc.)514/291, Plural hetero atoms in the tricyclo ring system514/457, Coumarins (including hydrogenated)514/513, C-C(=X)-X-C containing (X is chalcogen and at least one X is other than oxygen)514/538, Nitrogen bonded to carbon in Z moiety514/549, Z radical contains carbon to carbon unsaturation514/552, Z contains an unbroken chain of at least seven carbon atoms bonded directly to the C(=O) group514/554, Amine addition salt of the acid514/555, Benzene ring in acid moiety554/85, Sulfur containing554/101, Thioether, thiol, or mercaptide containing554/102, Plural sulfurs containing558/230, Esters having the thiocarboxylate group, -C(=X)X-, wherein the X's are the same or diverse chalcogens, with at least one X being sulfur, and wherein the single bonded X is bonded directly to an additional carbon, which carbon may be single bonded to any atom, but may be multiple bonded only to carbon558/256, Nitrogen attached indirectly to the -C(=O)S- group by acyclic nonionic bonding558/257, Benzene ring attached directly or indirectly to the -C(=0)S- group by nonionic bonding560/16, Nitrogen in acid moiety560/147, Sulfur in acid moiety560/153, Nitrogen or halogen in acid moiety562/426, Sulfur562/557Alpha N, beta S - acids or salts thereof
A method for the topical or systemic treatment of disorders mediated by proteases which result in skin or mucosal lesions, and in particular, pemphigus, cicatricial pemphigoid, bullous pemphigoid, lichen planus, and canker sores, is disclosed wherein the host is treated with an effective amount of N-acetyl ysteine or a derivative thereof, or its pharmaceutically acceptable salt, optionally in a pharmaceutically acceptable diluent or carrier for systemic or topical delivery.
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June 10, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
