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6-membered nitrogen-containing heteroaryl-oxazolidinones

Patent 5627181 Issued on May 6, 1997. Estimated Expiration Date: Icon_subject July 17, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
Patent #: 4705799
Issued on: 11/10/1987
Inventor: Gregory

Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
Patent #: 4801600
Issued on: 01/31/1989
Inventor: Wang ,   et al.

Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
Patent #: 4921869
Issued on: 05/01/1990
Inventor: Wang, et al.

Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
Patent #: 4965268
Issued on: 10/23/1990
Inventor: Wang, et al.

Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
Patent #: 5036092
Issued on: 07/30/1991
Inventor: Wang, et al.

Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents Patent #: 5254577
Issued on: 10/19/1993
Inventor: Carlson, et al.

Inventors

Application

No. 503369 filed on 07/17/1995

US Classes:

514/236.8, Ring chalcogen in the additional hetero ring (e.g., oxazole, etc.)514/340, Ring nitrogen in the additional hetero ring (e.g., oxazole, etc.)544/131, Double bonded divalent chalcogen containing544/238, 1,2-diazines which contain an additional hetero ring544/295, Plural diazine rings544/332, Chalcogen attached indirectly to the diazine ring by nonionic bonding544/336, 1,4-diazines544/356, Halogen or nitrogen attached directly to diazine ring carbon by nonionic bonding544/364, At least three hetero rings containing546/153, Chalcogen attached directly to the six-membered hetero ring by nonionic bonding546/159, Nitrogen, other than as nitro or nitroso, attached directly to the six membered hetero ring by nonionic bonding546/162, Nitrogen attached indirectly to the six-membered hetero ring through the directly attached nitrogen by nonionic bonding546/171, Nitrogen, other than as nitro or nitroso, attached directly to the carbocyclic ring of the quinoline ring system by nonionic bonding546/194, Carbocyclic ring containing546/256, Additional hetero ring containing546/268.7, Thiadiazoles (including hydrogenated)546/271.41,3-oxazoles (including hydrogenated)

Examiners

Primary: Ramsuer, Robert W.

Attorney, Agent or Firm

Foreign Patent References

  • 300272 EP. 01/13/1989
  • 0311090 EP. 04/13/1989
  • 0312000 EP. 04/13/1989
  • 0352781 EP. 01/13/1990
  • 0359418 EP. 03/13/1990
  • 0605729 EP. 07/13/1994
  • 9309103 WO. 05/13/1993
  • 9323384 WO. 11/13/1993

International Classes

A61K 031/44
A61K 031/535
C07D 413/04
C07D 413/14

Foreign Application Priority Data

1994-07-20 DE

Abstract

The invention relates to 6-membered nitrogen-containing heteroaryloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.

Other References

  • Borgulya, et al, Chemical Abstracts, vol. 123 (1995) No. 340097g
  • Patent Abstract of Japan, C, vol. 18, No. 291, Abstract of JP 6-56 802 (1994)
  • C-H. Park, et al., J. Med. Chem., vol. 35, No. 6, pp. 1156-1165, (1992)
  • I.T. Harrison, et al., "Compendium of Organic Synthetic Methods", vol. 1 and 2, Wiley-Interscience, New York, (1971
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